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- W2051250692 abstract "Amidines obtained from benzamides and DMF- or DMA-dimethylacetal were cyclized with phenylhydrazines to 3H- or 3-methyltriazoles. 3-Ethyltriazoles were synthesized from diacylamides. Triazole-3-carboxylic acides were prepared starting from anilines. The compounds were assayed in the rat adjuvant induced arthritis model. Some compounds show significant anti-inflammatory activity. 1,2,4-Triazole, 6. Mitt.1): Synthese von 3H-(bzw. Alkyl)-1,5-Diphenyl-1,2,4-triazolen und 1,5-Diphenyl-1H-1,2,4-triazol-3-carbonsäuren Die aus Benzamiden mit DMF-dimethylacetal darstellbaren Amidine lassen sich mit Phenylhydrazinen zu 3H-oder 3-methyl-triazolen cyclisieren. Die Synthese von 3-Ethyltriazole gelang aus Diacylamiden. Ausgehend von Anilinen wurden Triazol-3-carbonsäuren hergestellt. Einige dieser Verbindungen zeigten günstige antiphlogistische Aktivität im Adjuvans-Arthritis Test." @default.
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- W2051250692 date "1990-01-01" @default.
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- W2051250692 title "1,2,4-Triazoles, VI1): Synthesis of New 1,5-Diphenyl-3-H-1,2,4-triazoles Substituted with H-, Alkyl, or Carboxyl Groups at C-3" @default.
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- W2051250692 doi "https://doi.org/10.1002/ardp.19903230409" @default.
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