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• W2051251438 abstract "In eight patients who had previously responded to treatment with oral amiodarone for prevention of recurrent supraventricular paroxysmal tachycardia, a new regimen of oral amiodarone dosing was evaluated. Each patient received the entire dose, previously taken throughout one week (600 to 1,200mg), on a single day, once each week. After six weeks on this regimen, all patients were still free of arrhytmias and there were no adverse reactions to the drug. In the first week of the new treatment, amiodarone plasma levels gradually fell from 1.83 mg/l, to 0.48 mg/l, on average. The trough level was similar to that obtained when the drug was given on a daily basis. It is concluded that this new regimen can be used for patients receiving oral amiodarone, and it may be advantageous in improving the compliance of some patients." @default.
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• W2051251438 date "1983-11-01" @default.
• W2051251438 modified "2023-09-26" @default.
• W2051251438 title "Amiodarone in the antiarrhythmic therapy" @default.
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• W2051251438 doi "https://doi.org/10.1016/s0031-6989(83)80019-8" @default.
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