FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051254298> ?p ?o ?g. }

• W2051254298 endingPage "490" @default.
• W2051254298 startingPage "481" @default.
• W2051254298 abstract "A specific form of Transcranial Electrostimulation Treatment (TCET) has been shown to induce analgesia, alleviate symptoms of opiate withdrawal and alter nociceptive responses in neurons in the midbrain and hypothalamus of rats. TCET consists of a 10Hz, charge balanced, 10 mu A current passed for 30 minutes between electrodes placed in the ears. Both serotonin (5HT) and endogenous opioids have been strongly implicated in TCET responses. This study directly measured brain levels of several neurotransmitters and their metabolites in anesthetized rats stimulated with either 10 mu A TCET or 0 mu A (Sham). Neurotransmitters measured in selected homogenized brain areas by high performance liquid chromatography were 5HT and its metabolite, 5-hydroxyindolacetic acid (5HIAA); norepinephrine (NE) and its metabolite, 3-methoxy-4-hydroxyphenethyleneglycol (MHPG); and dopamine (DA). Levels of NE and DA were significantly higher in the hypothalamic region of TCET rats than of control rats. The midbrains of TCET rats contained significantly elevated levels of DA, MHPG, 5HT and 5HIAA. In the hindbrain no significant differences were observed. Thus, TCET appears to cause an increase in the synthesis or release of 5HT, DA and NE in the midbrain and DA and 5HT in the hypothalamus. In a separate experiment, beta-endorphin-like immunoreactivity was measured in blood plasma taken from rats at intervals before, during and after a 30 minute TCET treatment, but no demonstrable TCET effect was observed. The lack of change in serum endorphin levels suggests that TCET-induced opioid activity may be confined to the central nervous system, a reasonable theory because the current passes only through the head." @default.
• W2051254298 created "2016-06-24" @default.
• W2051254298 creator A5015321008 @default.
• W2051254298 creator A5019363396 @default.
• W2051254298 creator A5049577168 @default.
• W2051254298 creator A5056737493 @default.
• W2051254298 creator A5068569448 @default.
• W2051254298 date "1994-01-01" @default.
• W2051254298 modified "2023-09-24" @default.
• W2051254298 title "Transcranial electrostimulation effects on rat opioid and neurotransmitter levels" @default.
• W2051254298 cites W1684853394 @default.
• W2051254298 cites W1965721933 @default.
• W2051254298 cites W1974129689 @default.
• W2051254298 cites W1976679528 @default.
• W2051254298 cites W1979692529 @default.
• W2051254298 cites W1980532251 @default.
• W2051254298 cites W1981719166 @default.
• W2051254298 cites W1990048212 @default.
• W2051254298 cites W1990891726 @default.
• W2051254298 cites W1991149855 @default.
• W2051254298 cites W1993025875 @default.
• W2051254298 cites W1999286993 @default.
• W2051254298 cites W2007419927 @default.
• W2051254298 cites W2008381488 @default.
• W2051254298 cites W2009377725 @default.
• W2051254298 cites W2011245788 @default.
• W2051254298 cites W2013728417 @default.
• W2051254298 cites W2016417454 @default.
• W2051254298 cites W2016618854 @default.
• W2051254298 cites W2022208523 @default.
• W2051254298 cites W2024147111 @default.
• W2051254298 cites W2032167799 @default.
• W2051254298 cites W2036229347 @default.
• W2051254298 cites W2037060567 @default.
• W2051254298 cites W2041395144 @default.
• W2051254298 cites W2044028475 @default.
• W2051254298 cites W2044185289 @default.
• W2051254298 cites W2046408724 @default.
• W2051254298 cites W2064218234 @default.
• W2051254298 cites W2065160658 @default.
• W2051254298 cites W2068071475 @default.
• W2051254298 cites W2082214289 @default.
• W2051254298 cites W2085671304 @default.
• W2051254298 cites W2087454739 @default.
• W2051254298 cites W2092300386 @default.
• W2051254298 cites W2097814292 @default.
• W2051254298 cites W2138512124 @default.
• W2051254298 cites W2140350766 @default.
• W2051254298 cites W2177381548 @default.
• W2051254298 cites W2149724516 @default.
• W2051254298 doi "https://doi.org/10.1016/0024-3205(94)00407-2" @default.
• W2051254298 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7906003" @default.
• W2051254298 hasPublicationYear "1994" @default.
• W2051254298 type Work @default.
• W2051254298 sameAs 2051254298 @default.
• W2051254298 citedByCount "16" @default.
• W2051254298 countsByYear W20512542982012 @default.
• W2051254298 countsByYear W20512542982014 @default.
• W2051254298 countsByYear W20512542982016 @default.
• W2051254298 countsByYear W20512542982021 @default.
• W2051254298 crossrefType "journal-article" @default.
• W2051254298 hasAuthorship W2051254298A5015321008 @default.
• W2051254298 hasAuthorship W2051254298A5019363396 @default.
• W2051254298 hasAuthorship W2051254298A5049577168 @default.
• W2051254298 hasAuthorship W2051254298A5056737493 @default.
• W2051254298 hasAuthorship W2051254298A5068569448 @default.
• W2051254298 hasConcept C126322002 @default.
• W2051254298 hasConcept C134018914 @default.
• W2051254298 hasConcept C15490471 @default.
• W2051254298 hasConcept C170493617 @default.
• W2051254298 hasConcept C185592680 @default.
• W2051254298 hasConcept C187714386 @default.
• W2051254298 hasConcept C2775864247 @default.
• W2051254298 hasConcept C2776219046 @default.
• W2051254298 hasConcept C2777003273 @default.
• W2051254298 hasConcept C2777477808 @default.
• W2051254298 hasConcept C2778514916 @default.
• W2051254298 hasConcept C2781063702 @default.
• W2051254298 hasConcept C513476851 @default.
• W2051254298 hasConcept C529278444 @default.
• W2051254298 hasConcept C53910766 @default.
• W2051254298 hasConcept C552161191 @default.
• W2051254298 hasConcept C71924100 @default.
• W2051254298 hasConcept C88016717 @default.
• W2051254298 hasConceptScore W2051254298C126322002 @default.
• W2051254298 hasConceptScore W2051254298C134018914 @default.
• W2051254298 hasConceptScore W2051254298C15490471 @default.
• W2051254298 hasConceptScore W2051254298C170493617 @default.
• W2051254298 hasConceptScore W2051254298C185592680 @default.
• W2051254298 hasConceptScore W2051254298C187714386 @default.
• W2051254298 hasConceptScore W2051254298C2775864247 @default.
• W2051254298 hasConceptScore W2051254298C2776219046 @default.
• W2051254298 hasConceptScore W2051254298C2777003273 @default.
• W2051254298 hasConceptScore W2051254298C2777477808 @default.
• W2051254298 hasConceptScore W2051254298C2778514916 @default.
• W2051254298 hasConceptScore W2051254298C2781063702 @default.
• W2051254298 hasConceptScore W2051254298C513476851 @default.
• W2051254298 hasConceptScore W2051254298C529278444 @default.

• next