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• W2051258257 abstract "Recent studies have demonstrated that nicotine can enhance operant responding for other nonpharmacological reinforcing stimuli. However, the nature of the reinforcement-enhancing effect of nicotine remains largely unknown.The present study determined the dose dependency of the ability of nicotine to increase lever-pressing responses maintained by a compound visual stimulus (VS) in rats and examined its sensitivity to pharmacological antagonism of nicotinic acetylcholine receptors (nAChRs).Male Sprague-Dawley rats were trained in daily 1-h sessions to lever press for delivery of a VS (1 s lever light on and 60 s house light off) on a fixed ratio 5 schedule. During these sessions, eight scheduled response-independent intravenous infusions of nicotine (total amount: 0, 0.06, 0.12, 0.24, 0.48 mg kg(-1) h(-1)) were delivered. In pharmacological tests, a nonselective nAChR antagonist mecamylamine, alpha4beta2-selective antagonist dihydro-beta-erythroidine (DHbetaE), and alpha7-selective antagonist methyllycaconitine (MLA) were administered in different groups of rats 30 min before the session.The VS maintained a moderate level of lever-pressing responses and nicotine dose-dependently increased responses for the VS presentations. Preteatment of mecamylamine and DHbetaE but not MLA significantly attenuated the nicotine-enhanced responding. However, mecamylamine had no effect on responding for the VS in rats that received scheduled saline infusions.These results demonstrate dose dependency of the reinforcement-enhancing effect of nicotine and suggest that activation of the alpha4beta2- but not alpha7-containing nAChRs may mediate this effect." @default.
• W2051258257 created "2016-06-24" @default.
• W2051258257 creator A5013978633 @default.
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• W2051258257 creator A5025219266 @default.
• W2051258257 creator A5033981457 @default.
• W2051258257 creator A5085252579 @default.
• W2051258257 date "2007-07-08" @default.
• W2051258257 modified "2023-10-16" @default.
• W2051258257 title "Reinforcement enhancing effect of nicotine and its attenuation by nicotinic antagonists in rats" @default.
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• W2051258257 cites W1651595496 @default.
• W2051258257 cites W1820454600 @default.
• W2051258257 cites W1914592228 @default.
• W2051258257 cites W1935689631 @default.
• W2051258257 cites W1974110266 @default.
• W2051258257 cites W1975564949 @default.
• W2051258257 cites W1976328383 @default.
• W2051258257 cites W1978812850 @default.
• W2051258257 cites W1992440726 @default.
• W2051258257 cites W1992865170 @default.
• W2051258257 cites W1993640976 @default.
• W2051258257 cites W1995182242 @default.
• W2051258257 cites W2001283697 @default.
• W2051258257 cites W2001801891 @default.
• W2051258257 cites W2004216163 @default.
• W2051258257 cites W2004618736 @default.
• W2051258257 cites W2004634810 @default.
• W2051258257 cites W2007588418 @default.
• W2051258257 cites W2010770599 @default.
• W2051258257 cites W2011154525 @default.
• W2051258257 cites W2011596780 @default.
• W2051258257 cites W2019530923 @default.
• W2051258257 cites W2020432451 @default.
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• W2051258257 cites W2029680130 @default.
• W2051258257 cites W2032962758 @default.
• W2051258257 cites W2034769991 @default.
• W2051258257 cites W2035289099 @default.
• W2051258257 cites W2039694871 @default.
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• W2051258257 cites W2043130405 @default.
• W2051258257 cites W2050554540 @default.
• W2051258257 cites W2053407599 @default.
• W2051258257 cites W2055018246 @default.
• W2051258257 cites W2056899163 @default.
• W2051258257 cites W2059533109 @default.
• W2051258257 cites W2063187573 @default.
• W2051258257 cites W2066951615 @default.
• W2051258257 cites W2069860665 @default.
• W2051258257 cites W2070212982 @default.
• W2051258257 cites W2070593276 @default.
• W2051258257 cites W2072807276 @default.
• W2051258257 cites W2075869961 @default.
• W2051258257 cites W2076338351 @default.
• W2051258257 cites W2078241277 @default.
• W2051258257 cites W2078676430 @default.
• W2051258257 cites W2081950565 @default.
• W2051258257 cites W2087432957 @default.
• W2051258257 cites W2088168847 @default.
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• W2051258257 cites W2117726420 @default.
• W2051258257 cites W2139787666 @default.
• W2051258257 cites W2153089793 @default.
• W2051258257 cites W2159887246 @default.
• W2051258257 cites W2169105552 @default.
• W2051258257 cites W2265672234 @default.
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• W2051258257 doi "https://doi.org/10.1007/s00213-007-0863-3" @default.
• W2051258257 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2826146" @default.
• W2051258257 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17616849" @default.
• W2051258257 hasPublicationYear "2007" @default.
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