Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051259075> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2051259075 endingPage "45" @default.
- W2051259075 startingPage "42" @default.
- W2051259075 abstract "Galectins, a family of animal lectins that bind beta-galactoside sugar chains, are thought to have a variety of intra- and extracellular functions. Through a case-control study in the Japanese population and subsequent functional analyses, we previously showed that a functional single nucleotide polymorphism (SNP) in the gene encoding galectin-2 (lectin, galactoside-binding, soluble, 2; LGALS2) is associated with susceptibility to myocardial infarction. As an addition to the genetic information about LGALS2 reported earlier, we provide here a map of polymorphic sites within an 11-kb region containing the gene encoding a closely related molecule, galectin-1 (lectin, galactoside-binding, soluble, 1; LGALS1). The map includes 14 SNPs and two genetic variations of other types detected in a Japanese population sample. Five of the 14 SNPs were not among those deposited in the dbSNP database in the US National Center for Biotechnology Information and appeared to be novel. We also analyzed linkage disequilibrium (LD) using the 12 SNPs in which minor-allele frequencies were >0.20. Investigation of haplotype structure within the LGALS1 locus revealed five common haplotypes covering more than 95% of the test population. One, or a pair, of the SNPs described here might serve as a tag for detecting associations between complex diseases and genes in this local segment of chromosome 22q13.1." @default.
- W2051259075 created "2016-06-24" @default.
- W2051259075 creator A5030144869 @default.
- W2051259075 creator A5053237195 @default.
- W2051259075 creator A5079171795 @default.
- W2051259075 creator A5085142912 @default.
- W2051259075 date "2004-12-10" @default.
- W2051259075 modified "2023-10-14" @default.
- W2051259075 title "Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene" @default.
- W2051259075 cites W119023713 @default.
- W2051259075 cites W1591513747 @default.
- W2051259075 cites W1638424324 @default.
- W2051259075 cites W1968372807 @default.
- W2051259075 cites W1987555354 @default.
- W2051259075 cites W2037458235 @default.
- W2051259075 cites W2068470913 @default.
- W2051259075 cites W2069769149 @default.
- W2051259075 cites W2087550314 @default.
- W2051259075 cites W2093664978 @default.
- W2051259075 cites W2137570167 @default.
- W2051259075 cites W2146421447 @default.
- W2051259075 cites W2159026223 @default.
- W2051259075 doi "https://doi.org/10.1007/s10038-004-0218-4" @default.
- W2051259075 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15690107" @default.
- W2051259075 hasPublicationYear "2004" @default.
- W2051259075 type Work @default.
- W2051259075 sameAs 2051259075 @default.
- W2051259075 citedByCount "10" @default.
- W2051259075 countsByYear W20512590752012 @default.
- W2051259075 countsByYear W20512590752014 @default.
- W2051259075 countsByYear W20512590752022 @default.
- W2051259075 crossrefType "journal-article" @default.
- W2051259075 hasAuthorship W2051259075A5030144869 @default.
- W2051259075 hasAuthorship W2051259075A5053237195 @default.
- W2051259075 hasAuthorship W2051259075A5079171795 @default.
- W2051259075 hasAuthorship W2051259075A5085142912 @default.
- W2051259075 hasBestOaLocation W20512590751 @default.
- W2051259075 hasConcept C104317684 @default.
- W2051259075 hasConcept C135763542 @default.
- W2051259075 hasConcept C144024400 @default.
- W2051259075 hasConcept C149923435 @default.
- W2051259075 hasConcept C153209595 @default.
- W2051259075 hasConcept C163691529 @default.
- W2051259075 hasConcept C180754005 @default.
- W2051259075 hasConcept C197754878 @default.
- W2051259075 hasConcept C2908647359 @default.
- W2051259075 hasConcept C35605836 @default.
- W2051259075 hasConcept C35794970 @default.
- W2051259075 hasConcept C54355233 @default.
- W2051259075 hasConcept C55060382 @default.
- W2051259075 hasConcept C59701697 @default.
- W2051259075 hasConcept C84597430 @default.
- W2051259075 hasConcept C86803240 @default.
- W2051259075 hasConceptScore W2051259075C104317684 @default.
- W2051259075 hasConceptScore W2051259075C135763542 @default.
- W2051259075 hasConceptScore W2051259075C144024400 @default.
- W2051259075 hasConceptScore W2051259075C149923435 @default.
- W2051259075 hasConceptScore W2051259075C153209595 @default.
- W2051259075 hasConceptScore W2051259075C163691529 @default.
- W2051259075 hasConceptScore W2051259075C180754005 @default.
- W2051259075 hasConceptScore W2051259075C197754878 @default.
- W2051259075 hasConceptScore W2051259075C2908647359 @default.
- W2051259075 hasConceptScore W2051259075C35605836 @default.
- W2051259075 hasConceptScore W2051259075C35794970 @default.
- W2051259075 hasConceptScore W2051259075C54355233 @default.
- W2051259075 hasConceptScore W2051259075C55060382 @default.
- W2051259075 hasConceptScore W2051259075C59701697 @default.
- W2051259075 hasConceptScore W2051259075C84597430 @default.
- W2051259075 hasConceptScore W2051259075C86803240 @default.
- W2051259075 hasIssue "1" @default.
- W2051259075 hasLocation W20512590751 @default.
- W2051259075 hasLocation W20512590752 @default.
- W2051259075 hasOpenAccess W2051259075 @default.
- W2051259075 hasPrimaryLocation W20512590751 @default.
- W2051259075 hasRelatedWork W1966708416 @default.
- W2051259075 hasRelatedWork W2019989714 @default.
- W2051259075 hasRelatedWork W2071146638 @default.
- W2051259075 hasRelatedWork W2077572437 @default.
- W2051259075 hasRelatedWork W2087198772 @default.
- W2051259075 hasRelatedWork W2142009304 @default.
- W2051259075 hasRelatedWork W2168919926 @default.
- W2051259075 hasRelatedWork W2410452464 @default.
- W2051259075 hasRelatedWork W2954446872 @default.
- W2051259075 hasRelatedWork W4214574623 @default.
- W2051259075 hasVolume "50" @default.
- W2051259075 isParatext "false" @default.
- W2051259075 isRetracted "false" @default.
- W2051259075 magId "2051259075" @default.
- W2051259075 workType "article" @default.