FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051264241> ?p ?o ?g. }

• W2051264241 endingPage "35" @default.
• W2051264241 startingPage "30" @default.
• W2051264241 abstract "Enoxaparin is increasingly used for the anticoagulation of patients undergoing percutaneous coronary intervention (PCI) alone or in conjunction with GpIIb/IIIa platelet antagonists. The purpose of this study was to evaluate a newly developed HEMONOX point-of-care test (POCT) for monitoring the effect of enoxaparin in the presence or absence of GpIIb/IIIa antagonists during PCI. Patients received two consecutive doses of enoxaparin (total 0.5 mg/kg) separated by a 5-minute interval either alone (n = 21) or in combination with a GpIIb/IIIa inhibitor following standard practice (n = 18). POCT HEMONOX, traditional coagulation tests, and plasma anti-Xa chromogenic activity assay were performed at baseline and post bolus. HEMONOX clotting time (CT) at baseline was identical in the enoxaparin (69.0 ± 8.0 seconds) and enoxaparin/GpIIb/IIIa (71.0 ± 8.0 seconds) treatment groups. HEMONOX CT achieved peak value at 10 minutes post initial dose (P < 0.0001) and then decreased at sheath removal (60 minutes post bolus; P = 0.001) in the two groups. HEMONOX peak response varied among patients, ranging from 130 to 431 (enoxaparin) and 104 to 386 (enoxaparin/GpIIb/IIIa) seconds, which corresponded to therapeutic anti-Xa levels of 0.69-1.14 and 0.61-1.10 U/mL, respectively. Mean HEMONOX CT was reduced 50 seconds in the presence of GpIIb/IIIa antagonists, which was associated with a reduction of anti-Xa activity (P = 0.038) but remained within therapeutic range. GpIIb/IIIa treatment did not alter the correlation between HEMONOX CT and anti-Xa activity levels (r = 0.85 vs 0.84); eptifibatide and abciximab yielded the best correlation (r > 0.90). HEMONOX was the most sensitive monitoring POCT during PCI." @default.
• W2051264241 created "2016-06-24" @default.
• W2051264241 creator A5007859032 @default.
• W2051264241 creator A5044605776 @default.
• W2051264241 creator A5049240666 @default.
• W2051264241 creator A5052994249 @default.
• W2051264241 creator A5062287004 @default.
• W2051264241 creator A5064983817 @default.
• W2051264241 creator A5065553531 @default.
• W2051264241 creator A5076838351 @default.
• W2051264241 creator A5088241007 @default.
• W2051264241 date "2005-03-01" @default.
• W2051264241 modified "2023-09-27" @default.
• W2051264241 title "Point-of-Care Monitoring of Enoxaparin in the Presence of GpIIb/IIIa Combined Therapy During Percutaneous Coronary Interventions" @default.
• W2051264241 cites W1489383711 @default.
• W2051264241 cites W168034184 @default.
• W2051264241 cites W1970865244 @default.
• W2051264241 cites W1971881919 @default.
• W2051264241 cites W1987083415 @default.
• W2051264241 cites W2017132043 @default.
• W2051264241 cites W2018776013 @default.
• W2051264241 cites W2025703687 @default.
• W2051264241 cites W2026393945 @default.
• W2051264241 cites W2056489010 @default.
• W2051264241 cites W2059611663 @default.
• W2051264241 cites W2073146331 @default.
• W2051264241 cites W2075332638 @default.
• W2051264241 cites W2076677620 @default.
• W2051264241 cites W2086744615 @default.
• W2051264241 cites W2087914195 @default.
• W2051264241 cites W2101996111 @default.
• W2051264241 cites W2132540981 @default.
• W2051264241 cites W2149599987 @default.
• W2051264241 cites W2151340261 @default.
• W2051264241 cites W2161073476 @default.
• W2051264241 cites W2164353454 @default.
• W2051264241 cites W2316460201 @default.
• W2051264241 cites W3022148767 @default.
• W2051264241 doi "https://doi.org/10.1097/01.poc.0000157177.83327.3f" @default.
• W2051264241 hasPublicationYear "2005" @default.
• W2051264241 type Work @default.
• W2051264241 sameAs 2051264241 @default.
• W2051264241 citedByCount "2" @default.
• W2051264241 countsByYear W20512642412022 @default.
• W2051264241 crossrefType "journal-article" @default.
• W2051264241 hasAuthorship W2051264241A5007859032 @default.
• W2051264241 hasAuthorship W2051264241A5044605776 @default.
• W2051264241 hasAuthorship W2051264241A5049240666 @default.
• W2051264241 hasAuthorship W2051264241A5052994249 @default.
• W2051264241 hasAuthorship W2051264241A5062287004 @default.
• W2051264241 hasAuthorship W2051264241A5064983817 @default.
• W2051264241 hasAuthorship W2051264241A5065553531 @default.
• W2051264241 hasAuthorship W2051264241A5076838351 @default.
• W2051264241 hasAuthorship W2051264241A5088241007 @default.
• W2051264241 hasConcept C126322002 @default.
• W2051264241 hasConcept C141071460 @default.
• W2051264241 hasConcept C164705383 @default.
• W2051264241 hasConcept C2776884760 @default.
• W2051264241 hasConcept C2777987278 @default.
• W2051264241 hasConcept C2778205648 @default.
• W2051264241 hasConcept C2778825682 @default.
• W2051264241 hasConcept C2780400711 @default.
• W2051264241 hasConcept C2780868729 @default.
• W2051264241 hasConcept C42219234 @default.
• W2051264241 hasConcept C43376680 @default.
• W2051264241 hasConcept C45393284 @default.
• W2051264241 hasConcept C500558357 @default.
• W2051264241 hasConcept C71924100 @default.
• W2051264241 hasConcept C89560881 @default.
• W2051264241 hasConceptScore W2051264241C126322002 @default.
• W2051264241 hasConceptScore W2051264241C141071460 @default.
• W2051264241 hasConceptScore W2051264241C164705383 @default.
• W2051264241 hasConceptScore W2051264241C2776884760 @default.
• W2051264241 hasConceptScore W2051264241C2777987278 @default.
• W2051264241 hasConceptScore W2051264241C2778205648 @default.
• W2051264241 hasConceptScore W2051264241C2778825682 @default.
• W2051264241 hasConceptScore W2051264241C2780400711 @default.
• W2051264241 hasConceptScore W2051264241C2780868729 @default.
• W2051264241 hasConceptScore W2051264241C42219234 @default.
• W2051264241 hasConceptScore W2051264241C43376680 @default.
• W2051264241 hasConceptScore W2051264241C45393284 @default.
• W2051264241 hasConceptScore W2051264241C500558357 @default.
• W2051264241 hasConceptScore W2051264241C71924100 @default.
• W2051264241 hasConceptScore W2051264241C89560881 @default.
• W2051264241 hasIssue "1" @default.
• W2051264241 hasLocation W20512642411 @default.
• W2051264241 hasOpenAccess W2051264241 @default.
• W2051264241 hasPrimaryLocation W20512642411 @default.
• W2051264241 hasRelatedWork W1977637730 @default.
• W2051264241 hasRelatedWork W1978274741 @default.
• W2051264241 hasRelatedWork W2079494746 @default.
• W2051264241 hasRelatedWork W2101996111 @default.
• W2051264241 hasRelatedWork W2348852933 @default.
• W2051264241 hasRelatedWork W2375584960 @default.
• W2051264241 hasRelatedWork W2402026850 @default.
• W2051264241 hasRelatedWork W2761804449 @default.
• W2051264241 hasRelatedWork W2762524193 @default.
• W2051264241 hasRelatedWork W2905317511 @default.

• next