FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051265264> ?p ?o ?g. }

• W2051265264 endingPage "440" @default.
• W2051265264 startingPage "433" @default.
• W2051265264 abstract "The neurite outgrowth inhibitor protein Nogo is one of 300 proteins that contain a reticulon homology domain, which is responsible for their association with the endoplasmic reticulum. Here we have found that the Nogo-B spliceform becomes phosphorylated at Ser107 in response to lipopolysaccharide in RAW264 macrophages or anisomycin in HeLa cells. The phosphorylation is prevented by SB 203580, an inhibitor of SAPK2a (stress-activated protein kinase 2a)/p38a and SAPK2b/p38b, and does not occur in embryonic fibroblasts generated from SAPK2a/p38a-deficient mice. Nogo-B is phosphorylated at Ser107 in vitro by MAPKAP-K2 [MAPK (mitogen-activated protein kinase)-activated protein kinase-2] or MAPKAP-K3, but not by other protein kinases that are known to be activated by SAPK2a/p38a. The anisomycin-induced phosphorylation of Ser107 in HeLa cells can be prevented by 'knockdown' of MAPKAP-K2 using siRNA (small interfering RNA). Taken together, our results identify Nogo-B as a new physiological substrate of MAPKAP-K2." @default.
• W2051265264 created "2016-06-24" @default.
• W2051265264 creator A5010890113 @default.
• W2051265264 creator A5011449983 @default.
• W2051265264 creator A5025595864 @default.
• W2051265264 creator A5064241770 @default.
• W2051265264 creator A5081634444 @default.
• W2051265264 date "2005-10-10" @default.
• W2051265264 modified "2023-10-17" @default.
• W2051265264 title "Nogo-B is a new physiological substrate for MAPKAP-K2" @default.
• W2051265264 cites W1494491432 @default.
• W2051265264 cites W1500809101 @default.
• W2051265264 cites W1566502635 @default.
• W2051265264 cites W1566509581 @default.
• W2051265264 cites W1575276040 @default.
• W2051265264 cites W1587892340 @default.
• W2051265264 cites W1817417297 @default.
• W2051265264 cites W1952053031 @default.
• W2051265264 cites W1975974673 @default.
• W2051265264 cites W1977841940 @default.
• W2051265264 cites W1982123744 @default.
• W2051265264 cites W1986473192 @default.
• W2051265264 cites W1986570146 @default.
• W2051265264 cites W1988603521 @default.
• W2051265264 cites W1990099307 @default.
• W2051265264 cites W1990560133 @default.
• W2051265264 cites W1990707317 @default.
• W2051265264 cites W2003095417 @default.
• W2051265264 cites W2007435025 @default.
• W2051265264 cites W2011588737 @default.
• W2051265264 cites W2012846191 @default.
• W2051265264 cites W2017575850 @default.
• W2051265264 cites W2022914311 @default.
• W2051265264 cites W2032731042 @default.
• W2051265264 cites W2035454395 @default.
• W2051265264 cites W2037832555 @default.
• W2051265264 cites W2052750950 @default.
• W2051265264 cites W2056610728 @default.
• W2051265264 cites W2058176336 @default.
• W2051265264 cites W2063468575 @default.
• W2051265264 cites W2073238252 @default.
• W2051265264 cites W2090214297 @default.
• W2051265264 cites W2100712519 @default.
• W2051265264 cites W2111487813 @default.
• W2051265264 cites W2127551467 @default.
• W2051265264 cites W2133181350 @default.
• W2051265264 cites W2142847927 @default.
• W2051265264 cites W2869189 @default.
• W2051265264 cites W4211231247 @default.
• W2051265264 cites W4247904703 @default.
• W2051265264 doi "https://doi.org/10.1042/bj20050935" @default.
• W2051265264 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1276943" @default.
• W2051265264 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16095439" @default.
• W2051265264 hasPublicationYear "2005" @default.
• W2051265264 type Work @default.
• W2051265264 sameAs 2051265264 @default.
• W2051265264 citedByCount "30" @default.
• W2051265264 countsByYear W20512652642012 @default.
• W2051265264 countsByYear W20512652642013 @default.
• W2051265264 countsByYear W20512652642014 @default.
• W2051265264 countsByYear W20512652642015 @default.
• W2051265264 countsByYear W20512652642016 @default.
• W2051265264 countsByYear W20512652642017 @default.
• W2051265264 countsByYear W20512652642018 @default.
• W2051265264 countsByYear W20512652642019 @default.
• W2051265264 countsByYear W20512652642021 @default.
• W2051265264 countsByYear W20512652642022 @default.
• W2051265264 countsByYear W20512652642023 @default.
• W2051265264 crossrefType "journal-article" @default.
• W2051265264 hasAuthorship W2051265264A5010890113 @default.
• W2051265264 hasAuthorship W2051265264A5011449983 @default.
• W2051265264 hasAuthorship W2051265264A5025595864 @default.
• W2051265264 hasAuthorship W2051265264A5064241770 @default.
• W2051265264 hasAuthorship W2051265264A5081634444 @default.
• W2051265264 hasBestOaLocation W20512652642 @default.
• W2051265264 hasConcept C11960822 @default.
• W2051265264 hasConcept C153911025 @default.
• W2051265264 hasConcept C158617107 @default.
• W2051265264 hasConcept C184235292 @default.
• W2051265264 hasConcept C185592680 @default.
• W2051265264 hasConcept C2778073123 @default.
• W2051265264 hasConcept C51551487 @default.
• W2051265264 hasConcept C57074206 @default.
• W2051265264 hasConcept C86803240 @default.
• W2051265264 hasConcept C95444343 @default.
• W2051265264 hasConcept C97029542 @default.
• W2051265264 hasConceptScore W2051265264C11960822 @default.
• W2051265264 hasConceptScore W2051265264C153911025 @default.
• W2051265264 hasConceptScore W2051265264C158617107 @default.
• W2051265264 hasConceptScore W2051265264C184235292 @default.
• W2051265264 hasConceptScore W2051265264C185592680 @default.
• W2051265264 hasConceptScore W2051265264C2778073123 @default.
• W2051265264 hasConceptScore W2051265264C51551487 @default.
• W2051265264 hasConceptScore W2051265264C57074206 @default.
• W2051265264 hasConceptScore W2051265264C86803240 @default.
• W2051265264 hasConceptScore W2051265264C95444343 @default.
• W2051265264 hasConceptScore W2051265264C97029542 @default.
• W2051265264 hasIssue "2" @default.

• next