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- W2051267637 abstract "In this experiment, we used direct electron paramagnetic resonance (EPR) spectra to measure lipid peroxidation by hydroxyl radical (.OH), nitric oxide (.NO) and lipid radical (.L). NMDA-receptor associated lipid peroxidation is thought to act through .OH in induction of neurotoxicity. The origin of .OH generation was found to arise mainly from peroxynitrite anion produced from O(2)(-) and .NO rather than from Fenton's reaction. This study verified that .OH generation from interactive reactions between .NO and O(2)(-) initiates NMDA-induced lipid peroxidation of PC12 cells." @default.
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- W2051267637 date "2002-06-01" @default.
- W2051267637 modified "2023-10-18" @default.
- W2051267637 title "Nitric oxide and hydroxyl radicals initiate lipid peroxidation by NMDA receptor activation" @default.
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- W2051267637 doi "https://doi.org/10.1016/s0006-8993(02)02614-8" @default.
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