FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051267793> ?p ?o ?g. }

• W2051267793 endingPage "1378" @default.
• W2051267793 startingPage "1375" @default.
• W2051267793 abstract "Nardostachin, which is an iridoid isolated from Patrinia saniculaefolia, was examined by assessing its effect on the production of tumor necrosis factor-α (TNF-α) and expression of 2 enzymes, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), in lipopolysaccharide (LPS)-stimulated Raw264.7 macrophages. This compound consistently inhibited the production of nitric oxide (NO) and TNF-α production in a dose-dependent manner, with respective IC50 values of 12.3 and 16.2 μM. The decrease in quantity of NO products was accompanied by a decrease in the iNOS protein level, as assessed by Western blotting probed with specific anti-iNOS antibodies. In addition, this compound also reduced the COX-2 protein expression level and the attendant PGE2 production in LPS-stimulated macrophages. These results suggest that nardostachin may be useful for inhibiting the production of inflammatory mediators such as TNF-α, NO and PGE2 in inflammatory diseases." @default.
• W2051267793 created "2016-06-24" @default.
• W2051267793 creator A5019852528 @default.
• W2051267793 creator A5020253564 @default.
• W2051267793 creator A5033136222 @default.
• W2051267793 creator A5041813924 @default.
• W2051267793 creator A5044451426 @default.
• W2051267793 creator A5048293219 @default.
• W2051267793 creator A5054654340 @default.
• W2051267793 creator A5054998515 @default.
• W2051267793 creator A5079374959 @default.
• W2051267793 creator A5089260639 @default.
• W2051267793 date "2003-01-01" @default.
• W2051267793 modified "2023-09-25" @default.
• W2051267793 title "Inhibitory Effects of Nardostachin on Nitric Oxide, Prostaglandin E2, and Tumor Necrosis Factor-.ALPHA. Production in Lipopolysaccharide Activated Macrophages" @default.
• W2051267793 cites W1496717884 @default.
• W2051267793 cites W1500202490 @default.
• W2051267793 cites W1511086281 @default.
• W2051267793 cites W1560794427 @default.
• W2051267793 cites W1832498930 @default.
• W2051267793 cites W1983876074 @default.
• W2051267793 cites W1986917247 @default.
• W2051267793 cites W1993151749 @default.
• W2051267793 cites W1996013428 @default.
• W2051267793 cites W1999208756 @default.
• W2051267793 cites W2003546209 @default.
• W2051267793 cites W2040293110 @default.
• W2051267793 cites W2040790475 @default.
• W2051267793 cites W2064044677 @default.
• W2051267793 cites W2077195824 @default.
• W2051267793 cites W2084297801 @default.
• W2051267793 cites W2092763906 @default.
• W2051267793 cites W2093816949 @default.
• W2051267793 cites W2104878650 @default.
• W2051267793 cites W2106986352 @default.
• W2051267793 cites W2128160314 @default.
• W2051267793 cites W2130282385 @default.
• W2051267793 cites W2141685355 @default.
• W2051267793 doi "https://doi.org/10.1248/bpb.26.1375" @default.
• W2051267793 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14519938" @default.
• W2051267793 hasPublicationYear "2003" @default.
• W2051267793 type Work @default.
• W2051267793 sameAs 2051267793 @default.
• W2051267793 citedByCount "21" @default.
• W2051267793 countsByYear W20512677932012 @default.
• W2051267793 countsByYear W20512677932013 @default.
• W2051267793 countsByYear W20512677932014 @default.
• W2051267793 countsByYear W20512677932015 @default.
• W2051267793 countsByYear W20512677932017 @default.
• W2051267793 countsByYear W20512677932018 @default.
• W2051267793 countsByYear W20512677932019 @default.
• W2051267793 countsByYear W20512677932020 @default.
• W2051267793 crossrefType "journal-article" @default.
• W2051267793 hasAuthorship W2051267793A5019852528 @default.
• W2051267793 hasAuthorship W2051267793A5020253564 @default.
• W2051267793 hasAuthorship W2051267793A5033136222 @default.
• W2051267793 hasAuthorship W2051267793A5041813924 @default.
• W2051267793 hasAuthorship W2051267793A5044451426 @default.
• W2051267793 hasAuthorship W2051267793A5048293219 @default.
• W2051267793 hasAuthorship W2051267793A5054654340 @default.
• W2051267793 hasAuthorship W2051267793A5054998515 @default.
• W2051267793 hasAuthorship W2051267793A5079374959 @default.
• W2051267793 hasAuthorship W2051267793A5089260639 @default.
• W2051267793 hasBestOaLocation W20512677931 @default.
• W2051267793 hasConcept C104317684 @default.
• W2051267793 hasConcept C134018914 @default.
• W2051267793 hasConcept C153911025 @default.
• W2051267793 hasConcept C178790620 @default.
• W2051267793 hasConcept C17991360 @default.
• W2051267793 hasConcept C181199279 @default.
• W2051267793 hasConcept C185592680 @default.
• W2051267793 hasConcept C202751555 @default.
• W2051267793 hasConcept C2777622882 @default.
• W2051267793 hasConcept C2777956040 @default.
• W2051267793 hasConcept C2778754761 @default.
• W2051267793 hasConcept C2779244956 @default.
• W2051267793 hasConcept C2779689624 @default.
• W2051267793 hasConcept C519581460 @default.
• W2051267793 hasConcept C55493867 @default.
• W2051267793 hasConcept C85265743 @default.
• W2051267793 hasConcept C86803240 @default.
• W2051267793 hasConcept C98274493 @default.
• W2051267793 hasConceptScore W2051267793C104317684 @default.
• W2051267793 hasConceptScore W2051267793C134018914 @default.
• W2051267793 hasConceptScore W2051267793C153911025 @default.
• W2051267793 hasConceptScore W2051267793C178790620 @default.
• W2051267793 hasConceptScore W2051267793C17991360 @default.
• W2051267793 hasConceptScore W2051267793C181199279 @default.
• W2051267793 hasConceptScore W2051267793C185592680 @default.
• W2051267793 hasConceptScore W2051267793C202751555 @default.
• W2051267793 hasConceptScore W2051267793C2777622882 @default.
• W2051267793 hasConceptScore W2051267793C2777956040 @default.
• W2051267793 hasConceptScore W2051267793C2778754761 @default.
• W2051267793 hasConceptScore W2051267793C2779244956 @default.
• W2051267793 hasConceptScore W2051267793C2779689624 @default.
• W2051267793 hasConceptScore W2051267793C519581460 @default.
• W2051267793 hasConceptScore W2051267793C55493867 @default.
• W2051267793 hasConceptScore W2051267793C85265743 @default.

• next