FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051268728> ?p ?o ?g. }

• W2051268728 endingPage "80" @default.
• W2051268728 startingPage "75" @default.
• W2051268728 abstract "The objective of this study were: a) to investigate vitamin B12 deficiency among and advanced aged, clinically healthy, asymptomatic population, presumably with a high prevalence of vitamin B12 deficiency. This deficiency was defined as an increase in the MMA/creatinine ratio in urine and/or basal plasma HT levels which normalize after the administration of vitamin B12; b) its relationship with plasma vitamin B12 levels.A total of 45 subjects were studied, 19 in the Group of Gastrectomized patients, who were selected on the basis of an age over 60 years and partial gastrectomy of more than five years, and 26 in the Geriatric Group selected in two nursing homes. All of them were asymptopatic and healthy according to data in the clinical records and clinical examination, analytical studies, and none of them was taking any drug that might alter results. After basal analytical studies, which included B12, folates, metilmalonic acid/creatinine (MMA/creatinine) in urine and total plasma homocysteine (TH), i.m. vitamin B12 was administered for 15 days to the gastrectomized patients and oral B12 for 28 days with 2.5 mg folic acid for the last 14 days to the patients in the Geriatric Group. Basal analytical studies were repeated at the end of the study.Basal analytical studies were normal with the exception of two subjects with low levels of hemoglobin and 8 with decreased MCV. Only one subject had decreased serum cobalamines. Nine subjects (20%) were identified with increased basal levels of MMA/creatinine which normalized after decreasing between 97% and 12% after the administration of vitamin B12. TH and MCV also decreased significantly. Basal levels of vitamin B12 ranged from 244 pg/ml to 483 pg/ml (n = 220 pg/ml-980 pg/ml).Vitamin B12 deficiency, defined as an increase in the MMA/creatinine ratio and TH normalized with B12, is highly prevalent among elderly subjects and may occur in absence of clinical and/or analytical manifestations. Given the widespread recommendation of quantitating MMA and TH for the diagnosis of borderline cases of vitamin B12 deficiency, such disturbance may occur in clinically and biochemically normal subjects. Thus, a special caution should be exerted, given the existing comorbidity in advanced ages, before attributing B12 deficiency to a condition which may be the expression of another concomitant condition." @default.
• W2051268728 created "2016-06-24" @default.
• W2051268728 creator A5024595567 @default.
• W2051268728 creator A5031468414 @default.
• W2051268728 creator A5042489768 @default.
• W2051268728 creator A5063652146 @default.
• W2051268728 creator A5087851871 @default.
• W2051268728 date "2001-01-01" @default.
• W2051268728 modified "2023-10-01" @default.
• W2051268728 title "Estudio del déficit de cobalaminas en sujetos gastrectomizados y de edad avanzada" @default.
• W2051268728 cites W1497580828 @default.
• W2051268728 cites W1826900764 @default.
• W2051268728 cites W1900838714 @default.
• W2051268728 cites W1904131152 @default.
• W2051268728 cites W1953523985 @default.
• W2051268728 cites W1982519585 @default.
• W2051268728 cites W1985106590 @default.
• W2051268728 cites W1986101278 @default.
• W2051268728 cites W1991432170 @default.
• W2051268728 cites W1993228775 @default.
• W2051268728 cites W1997395669 @default.
• W2051268728 cites W1997421691 @default.
• W2051268728 cites W2000864446 @default.
• W2051268728 cites W2008325107 @default.
• W2051268728 cites W2009031512 @default.
• W2051268728 cites W2021156126 @default.
• W2051268728 cites W2029187079 @default.
• W2051268728 cites W2040603470 @default.
• W2051268728 cites W2044501461 @default.
• W2051268728 cites W2065349161 @default.
• W2051268728 cites W2067018203 @default.
• W2051268728 cites W2077058351 @default.
• W2051268728 cites W2077725073 @default.
• W2051268728 cites W2079550255 @default.
• W2051268728 cites W2080895280 @default.
• W2051268728 cites W2094455110 @default.
• W2051268728 cites W2112058501 @default.
• W2051268728 cites W2112469510 @default.
• W2051268728 cites W2113681646 @default.
• W2051268728 cites W2119262508 @default.
• W2051268728 cites W2131830106 @default.
• W2051268728 cites W2151667576 @default.
• W2051268728 cites W2321554768 @default.
• W2051268728 doi "https://doi.org/10.1016/s0014-2565(01)70754-0" @default.
• W2051268728 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11345609" @default.
• W2051268728 hasPublicationYear "2001" @default.
• W2051268728 type Work @default.
• W2051268728 sameAs 2051268728 @default.
• W2051268728 citedByCount "8" @default.
• W2051268728 countsByYear W20512687282012 @default.
• W2051268728 crossrefType "journal-article" @default.
• W2051268728 hasAuthorship W2051268728A5024595567 @default.
• W2051268728 hasAuthorship W2051268728A5031468414 @default.
• W2051268728 hasAuthorship W2051268728A5042489768 @default.
• W2051268728 hasAuthorship W2051268728A5063652146 @default.
• W2051268728 hasAuthorship W2051268728A5087851871 @default.
• W2051268728 hasConcept C126322002 @default.
• W2051268728 hasConcept C134018914 @default.
• W2051268728 hasConcept C2777910003 @default.
• W2051268728 hasConcept C2778024521 @default.
• W2051268728 hasConcept C2779306644 @default.
• W2051268728 hasConcept C2779750884 @default.
• W2051268728 hasConcept C2780026642 @default.
• W2051268728 hasConcept C2780306776 @default.
• W2051268728 hasConcept C2908647359 @default.
• W2051268728 hasConcept C71924100 @default.
• W2051268728 hasConcept C90924648 @default.
• W2051268728 hasConcept C99454951 @default.
• W2051268728 hasConceptScore W2051268728C126322002 @default.
• W2051268728 hasConceptScore W2051268728C134018914 @default.
• W2051268728 hasConceptScore W2051268728C2777910003 @default.
• W2051268728 hasConceptScore W2051268728C2778024521 @default.
• W2051268728 hasConceptScore W2051268728C2779306644 @default.
• W2051268728 hasConceptScore W2051268728C2779750884 @default.
• W2051268728 hasConceptScore W2051268728C2780026642 @default.
• W2051268728 hasConceptScore W2051268728C2780306776 @default.
• W2051268728 hasConceptScore W2051268728C2908647359 @default.
• W2051268728 hasConceptScore W2051268728C71924100 @default.
• W2051268728 hasConceptScore W2051268728C90924648 @default.
• W2051268728 hasConceptScore W2051268728C99454951 @default.
• W2051268728 hasIssue "2" @default.
• W2051268728 hasLocation W20512687281 @default.
• W2051268728 hasLocation W20512687282 @default.
• W2051268728 hasOpenAccess W2051268728 @default.
• W2051268728 hasPrimaryLocation W20512687281 @default.
• W2051268728 hasRelatedWork W1969550954 @default.
• W2051268728 hasRelatedWork W2009854143 @default.
• W2051268728 hasRelatedWork W2016328345 @default.
• W2051268728 hasRelatedWork W2044511036 @default.
• W2051268728 hasRelatedWork W2077325982 @default.
• W2051268728 hasRelatedWork W2115161226 @default.
• W2051268728 hasRelatedWork W2135024115 @default.
• W2051268728 hasRelatedWork W2150096959 @default.
• W2051268728 hasRelatedWork W2162653391 @default.
• W2051268728 hasRelatedWork W2411332413 @default.
• W2051268728 hasVolume "201" @default.
• W2051268728 isParatext "false" @default.
• W2051268728 isRetracted "false" @default.

• next