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- W2051269342 abstract "Most clotting factor VII (FVII)-deficient patients suffer from bleeding episodes and occasionally thromboembolic complications after surgical interventions or replacement therapy. However, thromboses without apparent triggering factors may occur as well. We report a case of a pregnant woman with inherited FVII deficiency and chronic vena porta thrombosis. She presented at 32 weeks of gestation with spontaneously increased international normalized ratio, severe thrombocytopenia and very few unspecific symptoms. The extensive examination of the patient revealed cavernous transformation of the portal vein with well expressed portosystemic collaterals, heterozygosity for three common polymorphisms in FVII gene, associated with reduction in plasma FVII levels, and no other factors predisposing to thrombosis." @default.
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- W2051269342 date "2010-04-01" @default.
- W2051269342 modified "2023-09-26" @default.
- W2051269342 title "Vena porta thrombosis in patient with inherited factor VII deficiency" @default.
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- W2051269342 doi "https://doi.org/10.1097/mbc.0b013e3283370166" @default.
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