Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051273202> ?p ?o ?g. }
- W2051273202 endingPage "142" @default.
- W2051273202 startingPage "135" @default.
- W2051273202 abstract "Thickening of the region adjacent to the basement membrane is a key component of the remodeling of the asthmatic airway and is caused by collagen deposition in the region.We sought to clarify the role of platelet-derived growth factor (PDGF), a competence factor of fibroblast, in the enhanced airway responsiveness and remodeling in a murine model.Diesel exhaust particulates (DEPs) were administered intranasally every other day for 2 weeks with or without anti-PDGF-beta neutralizing antibody or goat IgG. Pulmonary function was then analyzed by using whole-body plethysmography before and after acetylcholine inhalation.Anti-PDGF-beta neutralizing antibody significantly inhibited both the elevation of airway resistance elicited by 1.25 and 2.5 mg/mL acetylcholine and the increase in the airway wall thickening induced by DEPs. In addition, bronchoalveolar lavage fluid cell analysis revealed that anti-PDGF-beta neutralizing antibody did not affect cellular infiltration at the airways.PDGF plays an important role in the process of remodeling brought about by DEP exposure in mice." @default.
- W2051273202 created "2016-06-24" @default.
- W2051273202 creator A5009023927 @default.
- W2051273202 creator A5022776811 @default.
- W2051273202 creator A5031196806 @default.
- W2051273202 creator A5033607350 @default.
- W2051273202 creator A5033993541 @default.
- W2051273202 creator A5044991913 @default.
- W2051273202 creator A5046811190 @default.
- W2051273202 creator A5071241147 @default.
- W2051273202 creator A5073390666 @default.
- W2051273202 creator A5082008116 @default.
- W2051273202 date "2001-01-01" @default.
- W2051273202 modified "2023-09-26" @default.
- W2051273202 title "Platelet-derived growth factor is involved in the augmentation of airway responsiveness through remodeling of airways in diesel exhaust particulate–treated mice" @default.
- W2051273202 cites W1519494647 @default.
- W2051273202 cites W1900945426 @default.
- W2051273202 cites W1963534846 @default.
- W2051273202 cites W1974339560 @default.
- W2051273202 cites W1986535703 @default.
- W2051273202 cites W1990990168 @default.
- W2051273202 cites W1991246311 @default.
- W2051273202 cites W1995657953 @default.
- W2051273202 cites W1995674079 @default.
- W2051273202 cites W1999788260 @default.
- W2051273202 cites W2002211843 @default.
- W2051273202 cites W2005373658 @default.
- W2051273202 cites W2007687102 @default.
- W2051273202 cites W2011560227 @default.
- W2051273202 cites W2014216036 @default.
- W2051273202 cites W2015894555 @default.
- W2051273202 cites W2016025974 @default.
- W2051273202 cites W2023546187 @default.
- W2051273202 cites W2029084262 @default.
- W2051273202 cites W2030886221 @default.
- W2051273202 cites W2046661997 @default.
- W2051273202 cites W2049472311 @default.
- W2051273202 cites W2052140619 @default.
- W2051273202 cites W2062496772 @default.
- W2051273202 cites W2063203571 @default.
- W2051273202 cites W2070401283 @default.
- W2051273202 cites W2074649762 @default.
- W2051273202 cites W2079666008 @default.
- W2051273202 cites W2080764956 @default.
- W2051273202 cites W2089073177 @default.
- W2051273202 cites W2090375776 @default.
- W2051273202 cites W2094891357 @default.
- W2051273202 cites W2105038614 @default.
- W2051273202 cites W2111482500 @default.
- W2051273202 cites W2123537216 @default.
- W2051273202 cites W2131131671 @default.
- W2051273202 cites W2147532546 @default.
- W2051273202 cites W2154636701 @default.
- W2051273202 cites W2161972167 @default.
- W2051273202 cites W2165179802 @default.
- W2051273202 cites W2165586667 @default.
- W2051273202 cites W2168176836 @default.
- W2051273202 cites W2394694884 @default.
- W2051273202 doi "https://doi.org/10.1067/mai.2001.111433" @default.
- W2051273202 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11150003" @default.
- W2051273202 hasPublicationYear "2001" @default.
- W2051273202 type Work @default.
- W2051273202 sameAs 2051273202 @default.
- W2051273202 citedByCount "39" @default.
- W2051273202 countsByYear W20512732022012 @default.
- W2051273202 countsByYear W20512732022013 @default.
- W2051273202 countsByYear W20512732022015 @default.
- W2051273202 countsByYear W20512732022018 @default.
- W2051273202 countsByYear W20512732022019 @default.
- W2051273202 countsByYear W20512732022020 @default.
- W2051273202 countsByYear W20512732022021 @default.
- W2051273202 countsByYear W20512732022022 @default.
- W2051273202 crossrefType "journal-article" @default.
- W2051273202 hasAuthorship W2051273202A5009023927 @default.
- W2051273202 hasAuthorship W2051273202A5022776811 @default.
- W2051273202 hasAuthorship W2051273202A5031196806 @default.
- W2051273202 hasAuthorship W2051273202A5033607350 @default.
- W2051273202 hasAuthorship W2051273202A5033993541 @default.
- W2051273202 hasAuthorship W2051273202A5044991913 @default.
- W2051273202 hasAuthorship W2051273202A5046811190 @default.
- W2051273202 hasAuthorship W2051273202A5071241147 @default.
- W2051273202 hasAuthorship W2051273202A5073390666 @default.
- W2051273202 hasAuthorship W2051273202A5082008116 @default.
- W2051273202 hasBestOaLocation W20512732021 @default.
- W2051273202 hasConcept C105702510 @default.
- W2051273202 hasConcept C126322002 @default.
- W2051273202 hasConcept C170493617 @default.
- W2051273202 hasConcept C180361614 @default.
- W2051273202 hasConcept C203014093 @default.
- W2051273202 hasConcept C2775960820 @default.
- W2051273202 hasConcept C2776954882 @default.
- W2051273202 hasConcept C2777714996 @default.
- W2051273202 hasConcept C2777961210 @default.
- W2051273202 hasConcept C2781294074 @default.
- W2051273202 hasConcept C33362165 @default.
- W2051273202 hasConcept C71924100 @default.
- W2051273202 hasConceptScore W2051273202C105702510 @default.
- W2051273202 hasConceptScore W2051273202C126322002 @default.