Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051274258> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W2051274258 abstract "A 25-year old male, with a 3-year history of spastic paraparesis and a disturbance of bladder emptying, developed Addison's disease (plasma ACTH 1250 pg/ml, depressed cortisol values with loss of diurnal rhythm, potassium 6.8 mmol/l, sodium 123 mmol/l) associated with a urinary tract infection. The suspected diagnosis of adrenomyeloneuropathy was confirmed by the finding of raised plasma long-chain fatty acid concentrations. The patient was immediately given 0.4 mg fludrocortisone as a bolus, followed by 0.1 mg daily maintenance therapy, the urinary tract infection having already been successfully treated. Substitution therapy with hydrocortisone was also initiated (starting dose 30-20-10 mg daily, maintainance dose 20-10-5 mg daily). As a result, the electrolyte concentrations returned to normal and the neurological features improved. A family study was undertaken to determine whether the adrenomyeloneuropathy was an X-linked recessive form. Both the symptom-free mother (carrier) and the 19-year-old brother, who had suffered from Addison's disease since the third year of life, had raised plasma long-chain fatty acid concentrations. Both brothers were started on a diet low in long-chain fatty acids. Estimation of long-chain fatty acids is indicated in boys or young adult males with peripheral neuropathy or Addison's disease of uncertain aetiology." @default.
- W2051274258 created "2016-06-24" @default.
- W2051274258 creator A5017934514 @default.
- W2051274258 creator A5024910789 @default.
- W2051274258 creator A5028967076 @default.
- W2051274258 creator A5034393698 @default.
- W2051274258 creator A5083422759 @default.
- W2051274258 date "2008-03-25" @default.
- W2051274258 modified "2023-09-27" @default.
- W2051274258 title "Adrenomyeloneuropathie als Ursache eines Morbus Addison" @default.
- W2051274258 doi "https://doi.org/10.1055/s-2008-1063607" @default.
- W2051274258 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1993440" @default.
- W2051274258 hasPublicationYear "2008" @default.
- W2051274258 type Work @default.
- W2051274258 sameAs 2051274258 @default.
- W2051274258 citedByCount "0" @default.
- W2051274258 crossrefType "journal-article" @default.
- W2051274258 hasAuthorship W2051274258A5017934514 @default.
- W2051274258 hasAuthorship W2051274258A5024910789 @default.
- W2051274258 hasAuthorship W2051274258A5028967076 @default.
- W2051274258 hasAuthorship W2051274258A5034393698 @default.
- W2051274258 hasAuthorship W2051274258A5083422759 @default.
- W2051274258 hasConcept C126322002 @default.
- W2051274258 hasConcept C134018914 @default.
- W2051274258 hasConcept C137627325 @default.
- W2051274258 hasConcept C2776899810 @default.
- W2051274258 hasConcept C2777817097 @default.
- W2051274258 hasConcept C2778709874 @default.
- W2051274258 hasConcept C2779134260 @default.
- W2051274258 hasConcept C71924100 @default.
- W2051274258 hasConcept C77411442 @default.
- W2051274258 hasConcept C90924648 @default.
- W2051274258 hasConceptScore W2051274258C126322002 @default.
- W2051274258 hasConceptScore W2051274258C134018914 @default.
- W2051274258 hasConceptScore W2051274258C137627325 @default.
- W2051274258 hasConceptScore W2051274258C2776899810 @default.
- W2051274258 hasConceptScore W2051274258C2777817097 @default.
- W2051274258 hasConceptScore W2051274258C2778709874 @default.
- W2051274258 hasConceptScore W2051274258C2779134260 @default.
- W2051274258 hasConceptScore W2051274258C71924100 @default.
- W2051274258 hasConceptScore W2051274258C77411442 @default.
- W2051274258 hasConceptScore W2051274258C90924648 @default.
- W2051274258 hasLocation W20512742581 @default.
- W2051274258 hasLocation W20512742582 @default.
- W2051274258 hasOpenAccess W2051274258 @default.
- W2051274258 hasPrimaryLocation W20512742581 @default.
- W2051274258 hasRelatedWork W1520347299 @default.
- W2051274258 hasRelatedWork W1966088769 @default.
- W2051274258 hasRelatedWork W1981171782 @default.
- W2051274258 hasRelatedWork W2078224059 @default.
- W2051274258 hasRelatedWork W2090009791 @default.
- W2051274258 hasRelatedWork W2164405440 @default.
- W2051274258 hasRelatedWork W2192234344 @default.
- W2051274258 hasRelatedWork W2561276322 @default.
- W2051274258 hasRelatedWork W3138645314 @default.
- W2051274258 hasRelatedWork W4241864131 @default.
- W2051274258 isParatext "false" @default.
- W2051274258 isRetracted "false" @default.
- W2051274258 magId "2051274258" @default.
- W2051274258 workType "article" @default.