FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051277869> ?p ?o ?g. }

• W2051277869 endingPage "1390" @default.
• W2051277869 startingPage "1384" @default.
• W2051277869 abstract "Focal adhesion kinase plays a critical role in cancer progression, invasion, and metastasis. Although focal adhesion kinase overexpression indicates poor prognoses for hepatocellular carcinoma, its role in hepatocellular carcinoma metastasis has not been well investigated. In this study, 55 hepatocellular carcinoma patients were enrolled, and their primary liver tumors as well as 18 matched metastases were subjected to semiquantitative immunohistochemistry analysis of focal adhesion kinase expression. Overexpression of focal adhesion kinase was observed in 34 (61.8%) of 55 primary tumors and significantly predicted subsequent extrahepatic metastases (P = .04). Metastatic tumors expressed higher focal adhesion kinase than their matched primaries (P = .010). Focal adhesion kinase overexpression indicated both worse overall 5-year survival rate (51.5% ± 8.7% versus 90.2% ± 6.6%; P = .004) and 5-year progression-free survival rate (51.5% ± 8.7% versus 90.2% ± 6.6%; P = .041). Taken together, we demonstrated here that focal adhesion kinase expression is significantly related to subsequent hepatocellular carcinoma metastasis. Focal adhesion kinase is thus considered as a reasonable target for novel therapies against hepatocellular carcinoma progression and metastasis." @default.
• W2051277869 created "2016-06-24" @default.
• W2051277869 creator A5003144748 @default.
• W2051277869 creator A5021275887 @default.
• W2051277869 creator A5027837156 @default.
• W2051277869 creator A5050431009 @default.
• W2051277869 creator A5074026718 @default.
• W2051277869 creator A5084485772 @default.
• W2051277869 creator A5086809372 @default.
• W2051277869 date "2009-10-01" @default.
• W2051277869 modified "2023-09-26" @default.
• W2051277869 title "Overexpressed focal adhesion kinase predicts a higher incidence of extrahepatic metastasis and worse survival in hepatocellular carcinoma" @default.
• W2051277869 cites W1549544590 @default.
• W2051277869 cites W1577573926 @default.
• W2051277869 cites W1964376417 @default.
• W2051277869 cites W1967197989 @default.
• W2051277869 cites W1968893128 @default.
• W2051277869 cites W1971026364 @default.
• W2051277869 cites W1985961293 @default.
• W2051277869 cites W1986533360 @default.
• W2051277869 cites W2009378591 @default.
• W2051277869 cites W2014007705 @default.
• W2051277869 cites W2020215421 @default.
• W2051277869 cites W2029097287 @default.
• W2051277869 cites W2034558327 @default.
• W2051277869 cites W2042159031 @default.
• W2051277869 cites W2066367871 @default.
• W2051277869 cites W2069327540 @default.
• W2051277869 cites W2071368342 @default.
• W2051277869 cites W2088096911 @default.
• W2051277869 cites W2094395747 @default.
• W2051277869 cites W2095075235 @default.
• W2051277869 cites W2107130264 @default.
• W2051277869 cites W2111159494 @default.
• W2051277869 cites W2115100948 @default.
• W2051277869 cites W2127407977 @default.
• W2051277869 cites W2137052325 @default.
• W2051277869 cites W2147172608 @default.
• W2051277869 cites W2158319095 @default.
• W2051277869 cites W2165784890 @default.
• W2051277869 cites W2310034942 @default.
• W2051277869 cites W2917741034 @default.
• W2051277869 doi "https://doi.org/10.1016/j.humpath.2009.03.006" @default.
• W2051277869 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19454363" @default.
• W2051277869 hasPublicationYear "2009" @default.
• W2051277869 type Work @default.
• W2051277869 sameAs 2051277869 @default.
• W2051277869 citedByCount "26" @default.
• W2051277869 countsByYear W20512778692013 @default.
• W2051277869 countsByYear W20512778692014 @default.
• W2051277869 countsByYear W20512778692015 @default.
• W2051277869 countsByYear W20512778692016 @default.
• W2051277869 countsByYear W20512778692017 @default.
• W2051277869 countsByYear W20512778692018 @default.
• W2051277869 countsByYear W20512778692019 @default.
• W2051277869 countsByYear W20512778692020 @default.
• W2051277869 countsByYear W20512778692021 @default.
• W2051277869 countsByYear W20512778692022 @default.
• W2051277869 crossrefType "journal-article" @default.
• W2051277869 hasAuthorship W2051277869A5003144748 @default.
• W2051277869 hasAuthorship W2051277869A5021275887 @default.
• W2051277869 hasAuthorship W2051277869A5027837156 @default.
• W2051277869 hasAuthorship W2051277869A5050431009 @default.
• W2051277869 hasAuthorship W2051277869A5074026718 @default.
• W2051277869 hasAuthorship W2051277869A5084485772 @default.
• W2051277869 hasAuthorship W2051277869A5086809372 @default.
• W2051277869 hasConcept C108391706 @default.
• W2051277869 hasConcept C121608353 @default.
• W2051277869 hasConcept C126322002 @default.
• W2051277869 hasConcept C142724271 @default.
• W2051277869 hasConcept C151166631 @default.
• W2051277869 hasConcept C170493617 @default.
• W2051277869 hasConcept C178790620 @default.
• W2051277869 hasConcept C180361614 @default.
• W2051277869 hasConcept C185592680 @default.
• W2051277869 hasConcept C204232928 @default.
• W2051277869 hasConcept C2775960820 @default.
• W2051277869 hasConcept C2778019345 @default.
• W2051277869 hasConcept C2779013556 @default.
• W2051277869 hasConcept C2779256057 @default.
• W2051277869 hasConcept C502942594 @default.
• W2051277869 hasConcept C62478195 @default.
• W2051277869 hasConcept C71924100 @default.
• W2051277869 hasConcept C84416704 @default.
• W2051277869 hasConcept C86803240 @default.
• W2051277869 hasConcept C95444343 @default.
• W2051277869 hasConceptScore W2051277869C108391706 @default.
• W2051277869 hasConceptScore W2051277869C121608353 @default.
• W2051277869 hasConceptScore W2051277869C126322002 @default.
• W2051277869 hasConceptScore W2051277869C142724271 @default.
• W2051277869 hasConceptScore W2051277869C151166631 @default.
• W2051277869 hasConceptScore W2051277869C170493617 @default.
• W2051277869 hasConceptScore W2051277869C178790620 @default.
• W2051277869 hasConceptScore W2051277869C180361614 @default.
• W2051277869 hasConceptScore W2051277869C185592680 @default.
• W2051277869 hasConceptScore W2051277869C204232928 @default.
• W2051277869 hasConceptScore W2051277869C2775960820 @default.
• W2051277869 hasConceptScore W2051277869C2778019345 @default.

• next