FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051280277> ?p ?o ?g. }

• W2051280277 endingPage "622" @default.
• W2051280277 startingPage "617" @default.
• W2051280277 abstract "While the vasomotor effects of pCO(2) modulation are well documented, the influence of the carbon dioxide-bicarbonate system on the ischemia tolerance of brain tissue itself is controversial. Guinea-pig hippocampal tissue was subjected to ischemia simulation in an interface environment and examined electrophysiologically. Characteristics of anoxic depolarization as well as the postischemic recovery of evoked potentials were registered. During ischemia simulation, pH was changed and afterwards restored to 7.4. pH of 7.6 (n=6), and 7.8 (n=6) were adjusted by increasing bicarbonate concentration without changing pCO(2), while pH 8.2 was reached either with normal pCO(2) (n=8) or with zero CO(2) (n=9). pH 7.1 was created by doubling pCO(2) (n=22) or reducing bicarbonate (n=21), while acid pH of 6.9 (high pCO(2) and low bicarbonate) led to erratic measurements in the interface setup. Alkalotic conditions did not improve electrophysiological stability of the tissue, and pH 8.2 impeded the recovery of evoked potentials. Hypercarbic pH 7.1 led to significantly longer latency of depolarization while the same pH with lowered bicarbonate did not. Evoked potentials, however, recovered only partially after ischemia at hypercarbic pH 7.1. Once the tissue had recovered from anoxic depolarization at control pH, hypercarbic acidosis did not have any further protective effect when ischemia simulation was repeated (n=12). These results do not strengthen the concept of hyperventilation in intensive care, while they suggest a potential of hypercarbia within broader strategies delaying the onset of secondary brain damage." @default.
• W2051280277 created "2016-06-24" @default.
• W2051280277 creator A5013249676 @default.
• W2051280277 creator A5032197296 @default.
• W2051280277 creator A5035398643 @default.
• W2051280277 creator A5081323165 @default.
• W2051280277 creator A5084918739 @default.
• W2051280277 creator A5086778430 @default.
• W2051280277 date "2009-01-01" @default.
• W2051280277 modified "2023-10-16" @default.
• W2051280277 title "Influences of pCO2 and bicarbonate concentration on bioelectric phenomena in ischemic hippocampal ex vivo tissue" @default.
• W2051280277 cites W1487148446 @default.
• W2051280277 cites W1587224235 @default.
• W2051280277 cites W1603844893 @default.
• W2051280277 cites W188749348 @default.
• W2051280277 cites W1896790020 @default.
• W2051280277 cites W1964212152 @default.
• W2051280277 cites W1970412478 @default.
• W2051280277 cites W1974642350 @default.
• W2051280277 cites W1977894054 @default.
• W2051280277 cites W1986723404 @default.
• W2051280277 cites W1986910593 @default.
• W2051280277 cites W2001279193 @default.
• W2051280277 cites W2024085735 @default.
• W2051280277 cites W2024801871 @default.
• W2051280277 cites W2027862234 @default.
• W2051280277 cites W2030037936 @default.
• W2051280277 cites W2039387758 @default.
• W2051280277 cites W2042391571 @default.
• W2051280277 cites W2049221994 @default.
• W2051280277 cites W2066485803 @default.
• W2051280277 cites W2074261334 @default.
• W2051280277 cites W2075448078 @default.
• W2051280277 cites W2079933314 @default.
• W2051280277 cites W2081865527 @default.
• W2051280277 cites W2085431257 @default.
• W2051280277 cites W2087439174 @default.
• W2051280277 cites W2091867607 @default.
• W2051280277 cites W2093428170 @default.
• W2051280277 cites W2130493604 @default.
• W2051280277 cites W2130630814 @default.
• W2051280277 cites W2144759791 @default.
• W2051280277 cites W2158009878 @default.
• W2051280277 cites W2161056273 @default.
• W2051280277 cites W2229070028 @default.
• W2051280277 cites W2256025095 @default.
• W2051280277 cites W2396594432 @default.
• W2051280277 cites W2414288299 @default.
• W2051280277 cites W2418761006 @default.
• W2051280277 cites W2436948428 @default.
• W2051280277 doi "https://doi.org/10.1016/j.neuroscience.2008.10.001" @default.
• W2051280277 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18976691" @default.
• W2051280277 hasPublicationYear "2009" @default.
• W2051280277 type Work @default.
• W2051280277 sameAs 2051280277 @default.
• W2051280277 citedByCount "0" @default.
• W2051280277 crossrefType "journal-article" @default.
• W2051280277 hasAuthorship W2051280277A5013249676 @default.
• W2051280277 hasAuthorship W2051280277A5032197296 @default.
• W2051280277 hasAuthorship W2051280277A5035398643 @default.
• W2051280277 hasAuthorship W2051280277A5081323165 @default.
• W2051280277 hasAuthorship W2051280277A5084918739 @default.
• W2051280277 hasAuthorship W2051280277A5086778430 @default.
• W2051280277 hasConcept C126322002 @default.
• W2051280277 hasConcept C148762608 @default.
• W2051280277 hasConcept C185592680 @default.
• W2051280277 hasConcept C2777449187 @default.
• W2051280277 hasConcept C2778553927 @default.
• W2051280277 hasConcept C2781112554 @default.
• W2051280277 hasConcept C2909479059 @default.
• W2051280277 hasConcept C4141045 @default.
• W2051280277 hasConcept C42219234 @default.
• W2051280277 hasConcept C541997718 @default.
• W2051280277 hasConcept C71924100 @default.
• W2051280277 hasConceptScore W2051280277C126322002 @default.
• W2051280277 hasConceptScore W2051280277C148762608 @default.
• W2051280277 hasConceptScore W2051280277C185592680 @default.
• W2051280277 hasConceptScore W2051280277C2777449187 @default.
• W2051280277 hasConceptScore W2051280277C2778553927 @default.
• W2051280277 hasConceptScore W2051280277C2781112554 @default.
• W2051280277 hasConceptScore W2051280277C2909479059 @default.
• W2051280277 hasConceptScore W2051280277C4141045 @default.
• W2051280277 hasConceptScore W2051280277C42219234 @default.
• W2051280277 hasConceptScore W2051280277C541997718 @default.
• W2051280277 hasConceptScore W2051280277C71924100 @default.
• W2051280277 hasIssue "2" @default.
• W2051280277 hasLocation W20512802771 @default.
• W2051280277 hasLocation W20512802772 @default.
• W2051280277 hasOpenAccess W2051280277 @default.
• W2051280277 hasPrimaryLocation W20512802771 @default.
• W2051280277 hasRelatedWork W1994424364 @default.
• W2051280277 hasRelatedWork W2048985639 @default.
• W2051280277 hasRelatedWork W2051280277 @default.
• W2051280277 hasRelatedWork W2098446783 @default.
• W2051280277 hasRelatedWork W2396316249 @default.
• W2051280277 hasRelatedWork W2410112552 @default.
• W2051280277 hasRelatedWork W2421272188 @default.
• W2051280277 hasRelatedWork W2435854801 @default.

• next