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• W2051287378 endingPage "653" @default.
• W2051287378 startingPage "636" @default.
• W2051287378 abstract "Spinal anaesthesia is generally preferred for Caesarean section. Its superiority for the baby is often assumed. Umbilical artery acid-base status provides a valid index of fetal welfare. Twenty-seven studies reporting neonatal acid-base data with different types of anaesthesia were used to compare umbilical artery or vein pH and base deficit, using random-effect meta-analysis. Cord pH was significantly lower with spinal than with both general (difference: -0.015; 95% CI -0.029 to -0.001; 13 studies, 1272 subjects) and epidural anaesthesia (difference -0.013; 95% CI -0.024 to -0.002; 11 studies, 828 subjects). Larger doses of ephedrine contributed to the latter effect (p = 0.023). Sixteen studies reported a base deficit, which was significantly higher for spinal than for general (difference 1.109; 95% CI 0.434-1.784 mEq.l(-1); seven studies, 695 subject) and epidural anaesthesia (difference 0.910; 95% CI 0.222-1.598 mEq.l(-1); seven studies, 497 subjects). Spinal anaesthesia cannot be considered safer than epidural or general anaesthesia for the fetus." @default.
• W2051287378 created "2016-06-24" @default.
• W2051287378 creator A5013372591 @default.
• W2051287378 creator A5032448943 @default.
• W2051287378 date "2005-06-16" @default.
• W2051287378 modified "2023-10-17" @default.
• W2051287378 title "Anaesthesia for Caesarean section and neonatal acid-base status: a meta-analysis" @default.
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• W2051287378 doi "https://doi.org/10.1111/j.1365-2044.2005.04223.x" @default.
• W2051287378 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15960713" @default.
• W2051287378 hasPublicationYear "2005" @default.
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