FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051288982> ?p ?o ?g. }

• W2051288982 endingPage "924" @default.
• W2051288982 startingPage "919" @default.
• W2051288982 abstract "Glucocorticoids play an important role in cognitive function and act on glucocorticoid receptors and mineralocorticoid receptors (MRs) in the brain. Previously, the blockade of the MR has been shown to impair visuospatial and working memory in healthy young men. Here, we investigated the effects of the MR agonist fludrocortisone on memory in young and elderly healthy individuals. Thirty-one young (mean age 25.4 ± 4.6 years) and 22 elderly (mean age 63.2 ± 8.2 years) healthy participants received the MR agonist fludrocortisone (0.4 mg) or placebo at least 3 days apart in a randomized, double-blind within-subject cross-over design. We measured verbal memory (auditory verbal learning test), nonverbal memory (Rey/Taylor complex figure test), and working memory (digit-span task). As expected, young participants performed significantly better than elderly individuals in visuospatial memory (effect of group: F = 42.7, p < 0.01), verbal memory (F = 33.1, p < 0.01), and working memory (digit-span backward: F = 4.5, p = 0.04). For visuospatial memory (F = 5.0, p = 0.03) and short-term and working memory (digit-span forward: F = 4.2, p = 0.05), we found a significant treatment effect indicating better memory performance after fludrocortisone compared with placebo across groups. In concert with the previous studies, our data suggest a role of the MR in memory function. A cognitive enhancing effect by MR stimulation warrants future studies." @default.
• W2051288982 created "2016-06-24" @default.
• W2051288982 creator A5000705332 @default.
• W2051288982 creator A5018081371 @default.
• W2051288982 creator A5030243368 @default.
• W2051288982 creator A5030311579 @default.
• W2051288982 creator A5043039477 @default.
• W2051288982 creator A5043504486 @default.
• W2051288982 creator A5076311925 @default.
• W2051288982 date "2015-02-01" @default.
• W2051288982 modified "2023-10-13" @default.
• W2051288982 title "Stimulation of the mineralocorticoid receptor improves memory in young and elderly healthy individuals" @default.
• W2051288982 cites W1577035356 @default.
• W2051288982 cites W1596912882 @default.
• W2051288982 cites W1974162376 @default.
• W2051288982 cites W1981361333 @default.
• W2051288982 cites W1985525819 @default.
• W2051288982 cites W1986381796 @default.
• W2051288982 cites W1989994806 @default.
• W2051288982 cites W1993562836 @default.
• W2051288982 cites W1999974263 @default.
• W2051288982 cites W2003158170 @default.
• W2051288982 cites W2003976501 @default.
• W2051288982 cites W2006755029 @default.
• W2051288982 cites W2008290637 @default.
• W2051288982 cites W2009765361 @default.
• W2051288982 cites W2009824752 @default.
• W2051288982 cites W2010727732 @default.
• W2051288982 cites W2017586298 @default.
• W2051288982 cites W2022990742 @default.
• W2051288982 cites W2024518534 @default.
• W2051288982 cites W2024824460 @default.
• W2051288982 cites W2024844563 @default.
• W2051288982 cites W2026370575 @default.
• W2051288982 cites W2029404396 @default.
• W2051288982 cites W2033132308 @default.
• W2051288982 cites W2047810860 @default.
• W2051288982 cites W2053913437 @default.
• W2051288982 cites W2063808727 @default.
• W2051288982 cites W2070800054 @default.
• W2051288982 cites W2073726031 @default.
• W2051288982 cites W2079269482 @default.
• W2051288982 cites W2087921594 @default.
• W2051288982 cites W2089435641 @default.
• W2051288982 cites W2089614997 @default.
• W2051288982 cites W2093400617 @default.
• W2051288982 cites W2096607451 @default.
• W2051288982 cites W2100639159 @default.
• W2051288982 cites W2102178526 @default.
• W2051288982 cites W2103685082 @default.
• W2051288982 cites W2108460086 @default.
• W2051288982 cites W2110419377 @default.
• W2051288982 cites W2118251333 @default.
• W2051288982 cites W2123503571 @default.
• W2051288982 cites W2135539905 @default.
• W2051288982 cites W2148731425 @default.
• W2051288982 cites W2163704830 @default.
• W2051288982 cites W2165033322 @default.
• W2051288982 cites W2166623778 @default.
• W2051288982 cites W2169479929 @default.
• W2051288982 doi "https://doi.org/10.1016/j.neurobiolaging.2014.09.008" @default.
• W2051288982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25442112" @default.
• W2051288982 hasPublicationYear "2015" @default.
• W2051288982 type Work @default.
• W2051288982 sameAs 2051288982 @default.
• W2051288982 citedByCount "30" @default.
• W2051288982 countsByYear W20512889822015 @default.
• W2051288982 countsByYear W20512889822016 @default.
• W2051288982 countsByYear W20512889822017 @default.
• W2051288982 countsByYear W20512889822019 @default.
• W2051288982 countsByYear W20512889822020 @default.
• W2051288982 countsByYear W20512889822021 @default.
• W2051288982 countsByYear W20512889822022 @default.
• W2051288982 countsByYear W20512889822023 @default.
• W2051288982 crossrefType "journal-article" @default.
• W2051288982 hasAuthorship W2051288982A5000705332 @default.
• W2051288982 hasAuthorship W2051288982A5018081371 @default.
• W2051288982 hasAuthorship W2051288982A5030243368 @default.
• W2051288982 hasAuthorship W2051288982A5030311579 @default.
• W2051288982 hasAuthorship W2051288982A5043039477 @default.
• W2051288982 hasAuthorship W2051288982A5043504486 @default.
• W2051288982 hasAuthorship W2051288982A5076311925 @default.
• W2051288982 hasConcept C105641010 @default.
• W2051288982 hasConcept C126322002 @default.
• W2051288982 hasConcept C138496976 @default.
• W2051288982 hasConcept C142724271 @default.
• W2051288982 hasConcept C15744967 @default.
• W2051288982 hasConcept C169760540 @default.
• W2051288982 hasConcept C169900460 @default.
• W2051288982 hasConcept C170493617 @default.
• W2051288982 hasConcept C197268465 @default.
• W2051288982 hasConcept C204787440 @default.
• W2051288982 hasConcept C21963081 @default.
• W2051288982 hasConcept C27081682 @default.
• W2051288982 hasConcept C2776069600 @default.
• W2051288982 hasConcept C2776899810 @default.
• W2051288982 hasConcept C2778709874 @default.
• W2051288982 hasConcept C2778938600 @default.

• next