Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051289743> ?p ?o ?g. }
- W2051289743 endingPage "36" @default.
- W2051289743 startingPage "29" @default.
- W2051289743 abstract "In the present paper, the conditions required to improve the drug loading efficiency in biodegradable polymer particles prepared using the particular technique of freezing the inner water phase of the primary emulsion before preparation of the secondary emulsion were successfully optimized. The optimal freezing temperature for the inner water phase in the primary (w1/(o1 + o2)) emulsion, amount of oil soluble surfactant added to the outer o3 phase, and stirring rate and preparation time for the secondary (w1/(o1 + o2)/o3) emulsion, were determined to be −15 °C, 1.00 g, 400 rpm, and 10 s, respectively. PLGA particles with a smooth spherical morphology were achieved using a sub-zero temperature of −15 °C to freeze the inner water phase in the primary w1/(o1 + o2) emulsion. By utilizing this procedure, PLGA particles with a drug loading efficiency of approximately 60% were prepared in the liquid–liquid system, even though a low-molecular-weight hydrophilic drug (Mw = 137), isoniazid, was used." @default.
- W2051289743 created "2016-06-24" @default.
- W2051289743 creator A5020850244 @default.
- W2051289743 creator A5036974880 @default.
- W2051289743 creator A5038651727 @default.
- W2051289743 creator A5041117268 @default.
- W2051289743 creator A5084008957 @default.
- W2051289743 date "2012-05-01" @default.
- W2051289743 modified "2023-09-23" @default.
- W2051289743 title "Optimized preparation of biodegradable polymer particles encapsulating low-molecular-weight hydrophilic drugs" @default.
- W2051289743 cites W1966869310 @default.
- W2051289743 cites W1969338641 @default.
- W2051289743 cites W1970897698 @default.
- W2051289743 cites W1974918859 @default.
- W2051289743 cites W1974933001 @default.
- W2051289743 cites W1978443145 @default.
- W2051289743 cites W1980258733 @default.
- W2051289743 cites W1980903048 @default.
- W2051289743 cites W1990032110 @default.
- W2051289743 cites W1992928943 @default.
- W2051289743 cites W1993617075 @default.
- W2051289743 cites W1997923037 @default.
- W2051289743 cites W2001908731 @default.
- W2051289743 cites W2003999796 @default.
- W2051289743 cites W2004147064 @default.
- W2051289743 cites W2007670340 @default.
- W2051289743 cites W2021817350 @default.
- W2051289743 cites W2032735637 @default.
- W2051289743 cites W2032969057 @default.
- W2051289743 cites W2079245584 @default.
- W2051289743 cites W2084447009 @default.
- W2051289743 cites W2091516292 @default.
- W2051289743 cites W2094197620 @default.
- W2051289743 cites W2095172530 @default.
- W2051289743 cites W2147551987 @default.
- W2051289743 cites W2148198229 @default.
- W2051289743 cites W2163245582 @default.
- W2051289743 cites W2333955923 @default.
- W2051289743 doi "https://doi.org/10.1016/j.colsurfa.2012.03.014" @default.
- W2051289743 hasPublicationYear "2012" @default.
- W2051289743 type Work @default.
- W2051289743 sameAs 2051289743 @default.
- W2051289743 citedByCount "7" @default.
- W2051289743 countsByYear W20512897432013 @default.
- W2051289743 countsByYear W20512897432014 @default.
- W2051289743 countsByYear W20512897432015 @default.
- W2051289743 countsByYear W20512897432016 @default.
- W2051289743 countsByYear W20512897432018 @default.
- W2051289743 countsByYear W20512897432021 @default.
- W2051289743 crossrefType "journal-article" @default.
- W2051289743 hasAuthorship W2051289743A5020850244 @default.
- W2051289743 hasAuthorship W2051289743A5036974880 @default.
- W2051289743 hasAuthorship W2051289743A5038651727 @default.
- W2051289743 hasAuthorship W2051289743A5041117268 @default.
- W2051289743 hasAuthorship W2051289743A5084008957 @default.
- W2051289743 hasConcept C127413603 @default.
- W2051289743 hasConcept C155672457 @default.
- W2051289743 hasConcept C159985019 @default.
- W2051289743 hasConcept C171250308 @default.
- W2051289743 hasConcept C178790620 @default.
- W2051289743 hasConcept C185592680 @default.
- W2051289743 hasConcept C192562407 @default.
- W2051289743 hasConcept C2778123984 @default.
- W2051289743 hasConcept C2780165375 @default.
- W2051289743 hasConcept C42360764 @default.
- W2051289743 hasConcept C43617362 @default.
- W2051289743 hasConcept C44280652 @default.
- W2051289743 hasConcept C521977710 @default.
- W2051289743 hasConcept C58226133 @default.
- W2051289743 hasConceptScore W2051289743C127413603 @default.
- W2051289743 hasConceptScore W2051289743C155672457 @default.
- W2051289743 hasConceptScore W2051289743C159985019 @default.
- W2051289743 hasConceptScore W2051289743C171250308 @default.
- W2051289743 hasConceptScore W2051289743C178790620 @default.
- W2051289743 hasConceptScore W2051289743C185592680 @default.
- W2051289743 hasConceptScore W2051289743C192562407 @default.
- W2051289743 hasConceptScore W2051289743C2778123984 @default.
- W2051289743 hasConceptScore W2051289743C2780165375 @default.
- W2051289743 hasConceptScore W2051289743C42360764 @default.
- W2051289743 hasConceptScore W2051289743C43617362 @default.
- W2051289743 hasConceptScore W2051289743C44280652 @default.
- W2051289743 hasConceptScore W2051289743C521977710 @default.
- W2051289743 hasConceptScore W2051289743C58226133 @default.
- W2051289743 hasLocation W20512897431 @default.
- W2051289743 hasOpenAccess W2051289743 @default.
- W2051289743 hasPrimaryLocation W20512897431 @default.
- W2051289743 hasRelatedWork W1427301504 @default.
- W2051289743 hasRelatedWork W1965005336 @default.
- W2051289743 hasRelatedWork W2004693421 @default.
- W2051289743 hasRelatedWork W2069202186 @default.
- W2051289743 hasRelatedWork W2084237186 @default.
- W2051289743 hasRelatedWork W2176428484 @default.
- W2051289743 hasRelatedWork W2894391722 @default.
- W2051289743 hasRelatedWork W4206574953 @default.
- W2051289743 hasRelatedWork W4211249123 @default.
- W2051289743 hasRelatedWork W4214629883 @default.
- W2051289743 hasVolume "402" @default.
- W2051289743 isParatext "false" @default.