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- W2051312330 abstract "The bulk of the isolated nuclear chromosomal material, which is normally composed of rapidly sedimenting particles even though the DNA present is of relatively low molecular weight, can be obtained in a soluble form if a low ionic strength solution of chromatin∗ is sheared (Bonner et al., 1968; Zubay and Doty, 1959). However, a small limiting fraction of the nucleoprotein is insoluble even after extended shearing. We have inquired why this small fraction should be so resistant to solubilization by shearing. In this paper we shall show that the insoluble material consists of nucleohistone associated with a lipoprotein, a preliminary characterization of which is described." @default.
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- W2051312330 date "1968-10-01" @default.
- W2051312330 modified "2023-09-25" @default.
- W2051312330 title "A DNA-lipid protein containing material isolated from calf thymus nuclear chromatin" @default.
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- W2051312330 doi "https://doi.org/10.1016/0006-291x(68)90777-8" @default.
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