FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051345678> ?p ?o ?g. }

• W2051345678 endingPage "818" @default.
• W2051345678 startingPage "812" @default.
• W2051345678 abstract "A transgene inserted in euchromatin exhibits mosaic expression when targeted by a fusion protein made of the DNA-binding domain of GAL4 and the heterochromatin-associated protein HP1. The silencing responds to the loss of a dose of the dominant modifiers of position-effect variegation Su(var)3-7 and Su(var)2-5, the locus encoding HP1. The genomic environs of the insertion site at 87C1 comprise the dispersed repetitive elements micropia and alphagamma. In the presence of the GAL4-HP1 chimera, the polytene chromosomes of this line form loops between the insertion site of the transgene and six other sections of chromosome 3R, as well as, rarely, with pericentric and telomeric heterochromatin. In contrast to the insertion site of the transgene at 87C, the six loop-forming sites in the euchromatic arm were each previously described as intercalary heterochromatin. Moreover, GAL4-HP1 tethering on one homologue trans-inactivates the reporter on the other. HP1, probably together with other partners, could thus facilitate the coalescence of dispersed middle repetitive sequences, and organize the heterochromatic structure responsible for the variegated silencing of nearby euchromatic genes." @default.
• W2051345678 created "2016-06-24" @default.
• W2051345678 creator A5025108877 @default.
• W2051345678 creator A5030025550 @default.
• W2051345678 creator A5072764639 @default.
• W2051345678 creator A5084054622 @default.
• W2051345678 date "2001-02-15" @default.
• W2051345678 modified "2023-10-09" @default.
• W2051345678 title "Ectopic HP1 promotes chromosome loops and variegated silencing in Drosophila" @default.
• W2051345678 cites W1487669901 @default.
• W2051345678 cites W1575147957 @default.
• W2051345678 cites W1856601345 @default.
• W2051345678 cites W1964952136 @default.
• W2051345678 cites W1968789419 @default.
• W2051345678 cites W1971537513 @default.
• W2051345678 cites W1976616140 @default.
• W2051345678 cites W1978395898 @default.
• W2051345678 cites W1982453928 @default.
• W2051345678 cites W1985272204 @default.
• W2051345678 cites W1989687867 @default.
• W2051345678 cites W1991125055 @default.
• W2051345678 cites W2000826343 @default.
• W2051345678 cites W2001076830 @default.
• W2051345678 cites W2002532134 @default.
• W2051345678 cites W2005442184 @default.
• W2051345678 cites W2019273140 @default.
• W2051345678 cites W2020034373 @default.
• W2051345678 cites W2035169037 @default.
• W2051345678 cites W2035726721 @default.
• W2051345678 cites W2043471961 @default.
• W2051345678 cites W2055579158 @default.
• W2051345678 cites W2061032959 @default.
• W2051345678 cites W2067564842 @default.
• W2051345678 cites W2075259317 @default.
• W2051345678 cites W2079729858 @default.
• W2051345678 cites W2080791829 @default.
• W2051345678 cites W2084403120 @default.
• W2051345678 cites W2085297864 @default.
• W2051345678 cites W2091373076 @default.
• W2051345678 cites W2092403756 @default.
• W2051345678 cites W2094339092 @default.
• W2051345678 cites W2106642338 @default.
• W2051345678 cites W2123051193 @default.
• W2051345678 cites W2135002148 @default.
• W2051345678 cites W2139220897 @default.
• W2051345678 cites W2150201895 @default.
• W2051345678 cites W2152326948 @default.
• W2051345678 cites W2164715734 @default.
• W2051345678 cites W2189443081 @default.
• W2051345678 cites W2189453069 @default.
• W2051345678 cites W2240376651 @default.
• W2051345678 cites W2323289681 @default.
• W2051345678 cites W2417114846 @default.
• W2051345678 cites W303214814 @default.
• W2051345678 doi "https://doi.org/10.1093/emboj/20.4.812" @default.
• W2051345678 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/145414" @default.
• W2051345678 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11179225" @default.
• W2051345678 hasPublicationYear "2001" @default.
• W2051345678 type Work @default.
• W2051345678 sameAs 2051345678 @default.
• W2051345678 citedByCount "38" @default.
• W2051345678 countsByYear W20513456782013 @default.
• W2051345678 countsByYear W20513456782015 @default.
• W2051345678 countsByYear W20513456782016 @default.
• W2051345678 countsByYear W20513456782017 @default.
• W2051345678 countsByYear W20513456782019 @default.
• W2051345678 countsByYear W20513456782021 @default.
• W2051345678 crossrefType "journal-article" @default.
• W2051345678 hasAuthorship W2051345678A5025108877 @default.
• W2051345678 hasAuthorship W2051345678A5030025550 @default.
• W2051345678 hasAuthorship W2051345678A5072764639 @default.
• W2051345678 hasAuthorship W2051345678A5084054622 @default.
• W2051345678 hasBestOaLocation W20513456782 @default.
• W2051345678 hasConcept C100924687 @default.
• W2051345678 hasConcept C103435993 @default.
• W2051345678 hasConcept C104317684 @default.
• W2051345678 hasConcept C125215638 @default.
• W2051345678 hasConcept C153911025 @default.
• W2051345678 hasConcept C30481170 @default.
• W2051345678 hasConcept C54355233 @default.
• W2051345678 hasConcept C72391661 @default.
• W2051345678 hasConcept C86803240 @default.
• W2051345678 hasConcept C92149661 @default.
• W2051345678 hasConceptScore W2051345678C100924687 @default.
• W2051345678 hasConceptScore W2051345678C103435993 @default.
• W2051345678 hasConceptScore W2051345678C104317684 @default.
• W2051345678 hasConceptScore W2051345678C125215638 @default.
• W2051345678 hasConceptScore W2051345678C153911025 @default.
• W2051345678 hasConceptScore W2051345678C30481170 @default.
• W2051345678 hasConceptScore W2051345678C54355233 @default.
• W2051345678 hasConceptScore W2051345678C72391661 @default.
• W2051345678 hasConceptScore W2051345678C86803240 @default.
• W2051345678 hasConceptScore W2051345678C92149661 @default.
• W2051345678 hasIssue "4" @default.
• W2051345678 hasLocation W20513456781 @default.
• W2051345678 hasLocation W20513456782 @default.
• W2051345678 hasLocation W20513456783 @default.
• W2051345678 hasLocation W20513456784 @default.

• next