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- W2051427472 endingPage "1911" @default.
- W2051427472 startingPage "1901" @default.
- W2051427472 abstract "Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming one of most common liver diseases in industrialized countries owing to the increasing prevalence of obesity and being overweight. Until now, loss of weight and physical activity have represented the cornerstone of treatment, but they are very difficult to achieve and to maintain. Therefore, new treatments based on pathogenetic mechanisms leading to NAFLD are under evaluation to establish an effective pharmacological therapy for this disorder.An overview of current therapeutic interventions to treat NAFLD is given. This review provides evidence of the efficacy of natural and pharmacological agents used so far in the treatment of both adult and pediatric NAFLD, on the basis of clinical trials published in the last 10 years.In the last 10 years, many pharmacological agents on the basis of the pathogenetic mechanism of NAFLD have been attempted, but so far guidelines for the management of NAFLD are lacking. We believe that the advance in the understanding of pathogenesis and factors involved in the progression of the disease may disclose the way to defining new, solid, therapeutic strategies. A multidisciplinary approach considering the risk factors and comorbidities of fatty liver will represent in the future a successful therapeutic strategy for NAFLD." @default.
- W2051427472 created "2016-06-24" @default.
- W2051427472 creator A5011467033 @default.
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- W2051427472 creator A5046479230 @default.
- W2051427472 creator A5061728147 @default.
- W2051427472 creator A5075835057 @default.
- W2051427472 date "2011-06-04" @default.
- W2051427472 modified "2023-09-23" @default.
- W2051427472 title "Expert opinion on current therapies for nonalcoholic fatty liver disease" @default.
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