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- W2051440750 abstract "Signal transduction mediated by the single yeast isozyme of protein kinase C (Pkc1p) is essential for the maintenance of cellular integrity in this model eukaryote. The past few years have seen a dramatic increase in our knowledge of the upstream regulatory factors that modulate Pkc1p activity (e.g. Tor2p, Rom1p, Rom2p, Rho1p, Slg1p, Mid2p) and of the downstream targets of the MAP kinase cascade triggered by it (e.g. Rlm1p, SBF complex). The picture that has emerged connects this pathway to a variety of other cellular processes, such as cell cycle progression (Cdc28p, Swi4p), mating (Ste20p), nutrient sensing (Ira1p), calcium homeostasis (calcineurin, Mid2p, Fks2p) and the structural dynamics of the cytoskeleton (Spa1p, Bni1p)." @default.
- W2051440750 created "2016-06-24" @default.
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- W2051440750 creator A5052440161 @default.
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- W2051440750 date "1999-05-01" @default.
- W2051440750 modified "2023-10-15" @default.
- W2051440750 title "The protein kinase C-mediated MAP kinase pathway involved in the maintenance of cellular integrity in Saccharomyces cerevisiae" @default.
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- W2051440750 doi "https://doi.org/10.1046/j.1365-2958.1999.01375.x" @default.
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