Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051503669> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2051503669 endingPage "263" @default.
- W2051503669 startingPage "253" @default.
- W2051503669 abstract "By examining microtubule regrowth using immunofluorescence with antibody to tubulin, we have studied the structure and intracellular localization of microtubule initiation sites in undifferentiated and differentiated mouse neuroblastoma cells. The undifferentiated cells are round and lack cell processes. They contain an average of 12 initiation sites per cell. Each of these sites, which are located near the cell nucleus, initiates the growth of several microtubules in a radial formation. In contrast to the undifferentiated cells, neuroblastoma cells stimulated to differentiate by serum deprivation are asymmetrical, containing one or two very long neurites. These cells have a single, large microtubule initiation center which can be visualized not only by immunofluorescence but by phase-contrast and differential interference microscopy as well. The initiation site measures 3-4 mu in diameter and is located in the cell body along a line defined by the neurite. During cell differentiation, the large initiation, the large initiation center seems to be formed by the aggregation of many smaller sites. This process procedes neurite extension by about 24 hr. The growth of microtubules from this center appears to be highly oriented, since most microtubules initially grow into the neurite processes rather than into the cell interior. Thus major changes in the structure and location of microtubule initiation sites occur during the differentiation of neuroblastoma cells. Similar changes are likely to be involved in alterations in the morphology of other cell types." @default.
- W2051503669 created "2016-06-24" @default.
- W2051503669 creator A5015176214 @default.
- W2051503669 creator A5022918796 @default.
- W2051503669 creator A5026952730 @default.
- W2051503669 date "1979-02-01" @default.
- W2051503669 modified "2023-09-27" @default.
- W2051503669 title "Aggregation of microtubule initiation sites preceding neurite outgrowth in mouse neuroblastoma cells" @default.
- W2051503669 cites W1994765036 @default.
- W2051503669 cites W2006660988 @default.
- W2051503669 cites W2012874302 @default.
- W2051503669 cites W2018152992 @default.
- W2051503669 cites W2090772762 @default.
- W2051503669 cites W2092915182 @default.
- W2051503669 cites W2093063761 @default.
- W2051503669 cites W2121637864 @default.
- W2051503669 cites W2150382846 @default.
- W2051503669 doi "https://doi.org/10.1016/0092-8674(79)90003-5" @default.
- W2051503669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/455435" @default.
- W2051503669 hasPublicationYear "1979" @default.
- W2051503669 type Work @default.
- W2051503669 sameAs 2051503669 @default.
- W2051503669 citedByCount "110" @default.
- W2051503669 countsByYear W20515036692016 @default.
- W2051503669 countsByYear W20515036692022 @default.
- W2051503669 crossrefType "journal-article" @default.
- W2051503669 hasAuthorship W2051503669A5015176214 @default.
- W2051503669 hasAuthorship W2051503669A5022918796 @default.
- W2051503669 hasAuthorship W2051503669A5026952730 @default.
- W2051503669 hasConcept C104317684 @default.
- W2051503669 hasConcept C10447061 @default.
- W2051503669 hasConcept C104672736 @default.
- W2051503669 hasConcept C109986877 @default.
- W2051503669 hasConcept C113246987 @default.
- W2051503669 hasConcept C142724271 @default.
- W2051503669 hasConcept C147080431 @default.
- W2051503669 hasConcept C148738053 @default.
- W2051503669 hasConcept C1491633281 @default.
- W2051503669 hasConcept C159654299 @default.
- W2051503669 hasConcept C202751555 @default.
- W2051503669 hasConcept C203014093 @default.
- W2051503669 hasConcept C20418707 @default.
- W2051503669 hasConcept C2776715637 @default.
- W2051503669 hasConcept C2778236600 @default.
- W2051503669 hasConcept C29537977 @default.
- W2051503669 hasConcept C54355233 @default.
- W2051503669 hasConcept C61081601 @default.
- W2051503669 hasConcept C71924100 @default.
- W2051503669 hasConcept C79879829 @default.
- W2051503669 hasConcept C81885089 @default.
- W2051503669 hasConcept C84425145 @default.
- W2051503669 hasConcept C86803240 @default.
- W2051503669 hasConcept C95444343 @default.
- W2051503669 hasConceptScore W2051503669C104317684 @default.
- W2051503669 hasConceptScore W2051503669C10447061 @default.
- W2051503669 hasConceptScore W2051503669C104672736 @default.
- W2051503669 hasConceptScore W2051503669C109986877 @default.
- W2051503669 hasConceptScore W2051503669C113246987 @default.
- W2051503669 hasConceptScore W2051503669C142724271 @default.
- W2051503669 hasConceptScore W2051503669C147080431 @default.
- W2051503669 hasConceptScore W2051503669C148738053 @default.
- W2051503669 hasConceptScore W2051503669C1491633281 @default.
- W2051503669 hasConceptScore W2051503669C159654299 @default.
- W2051503669 hasConceptScore W2051503669C202751555 @default.
- W2051503669 hasConceptScore W2051503669C203014093 @default.
- W2051503669 hasConceptScore W2051503669C20418707 @default.
- W2051503669 hasConceptScore W2051503669C2776715637 @default.
- W2051503669 hasConceptScore W2051503669C2778236600 @default.
- W2051503669 hasConceptScore W2051503669C29537977 @default.
- W2051503669 hasConceptScore W2051503669C54355233 @default.
- W2051503669 hasConceptScore W2051503669C61081601 @default.
- W2051503669 hasConceptScore W2051503669C71924100 @default.
- W2051503669 hasConceptScore W2051503669C79879829 @default.
- W2051503669 hasConceptScore W2051503669C81885089 @default.
- W2051503669 hasConceptScore W2051503669C84425145 @default.
- W2051503669 hasConceptScore W2051503669C86803240 @default.
- W2051503669 hasConceptScore W2051503669C95444343 @default.
- W2051503669 hasIssue "2" @default.
- W2051503669 hasLocation W20515036691 @default.
- W2051503669 hasLocation W20515036692 @default.
- W2051503669 hasOpenAccess W2051503669 @default.
- W2051503669 hasPrimaryLocation W20515036691 @default.
- W2051503669 hasRelatedWork W1869941631 @default.
- W2051503669 hasRelatedWork W1893566722 @default.
- W2051503669 hasRelatedWork W2051503669 @default.
- W2051503669 hasRelatedWork W2060648951 @default.
- W2051503669 hasRelatedWork W2075366096 @default.
- W2051503669 hasRelatedWork W2080175123 @default.
- W2051503669 hasRelatedWork W2094511161 @default.
- W2051503669 hasRelatedWork W2973312646 @default.
- W2051503669 hasRelatedWork W3005078839 @default.
- W2051503669 hasRelatedWork W948219868 @default.
- W2051503669 hasVolume "16" @default.
- W2051503669 isParatext "false" @default.
- W2051503669 isRetracted "false" @default.
- W2051503669 magId "2051503669" @default.
- W2051503669 workType "article" @default.