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• W2051504268 abstract "<b>Background</b> EMPHASIS10 is a novel, easy to use quality of life questionnaire designed for patients with pulmonary hypertension (PH) <b>^<i>1</i></b>. We report our experience in using this score and its relation to markers of disease severity. <b>Methods and Results</b> In total, n=174 patients completed the EMPHASIS10; patients with learning difficulties were excluded. Median age [interquartile range] was 47[38-58] years and 122(70%) were female. PH diagnosis included 20(11%) patients with iPAH or heritable PAH, 97(56%) with PAH related to CHD, 22(13%) patients with PAH due to connective tissue disease and 35(20%) with other types of PH. EMPHASIS10 consists of 10 questions, each graded on a semantic differential six-point scale (0 to 5), for a maximum achievable (worse possible) score of 50. Median EMPHASIS10 score was 23[12-33]. No significant association with gender or oxygen saturation was seen. In contrast, patients in higher WHO functional class had significantly worse score (13.0[5.0-23.5] in FC I-II vs 31[22-37] in FC III-IV, p<0.001). Also, a strong correlation between EMPHASIS10 score and 6MWT distance (R=0.58, p<0.001) was observed. <b>Conclusion:</b> The EMPHASIS10 score is significantly associated with established predictors of exercise intolerance and prognosis. Further studies are needed to provide cut-offs which can be used to introduce or escalate disease specific therapies in PH. Yorke J et al.ERJ2014;43,1106-1113." @default.
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• W2051504268 date "2014-07-15" @default.
• W2051504268 modified "2023-09-23" @default.
• W2051504268 title "Surgeon who referred girlfriend to gynaecologist has suspension revoked" @default.
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• W2051504268 doi "https://doi.org/10.1136/bmj.g4636" @default.
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