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- W2051558704 abstract "The calcium channel blocker, nicardipine (100 ng/ml) markedly antagonized the coronary vasoconstrictor effect of the peptide leukotrienes LTC4 and LTD4 on the isolated perfused cat coronary artery. However, nicardipine even at 300 ng/ml failed to antagonize the leukotriene induced contraction of either tracheal or pulmonary parenchymal strips from guinea pigs. However, at higher concentrations (i.e., 10 micrograms/ml), nicardipine inhibited the production of peptide leukotrienes from minced cat lung incubated in the presence of A23187. Thus, nicardipine exerts some selectivity in its anti-leukotriene actions." @default.
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- W2051558704 date "1984-12-01" @default.
- W2051558704 modified "2023-10-16" @default.
- W2051558704 title "Specificity of anti-leukotriene actions of nicardipine" @default.
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- W2051558704 doi "https://doi.org/10.1016/s0031-6989(84)80079-x" @default.
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