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- W2051579237 abstract "From a mouse hybridoma cell line secreting a monoclonal antibody directed against the tumour marker human placental alkaline phosphatase, mRNA coding for the H and L chains of this antibody was isolated and cloned as cDNA. Sequence analysis of the H and L chain cDNAs confirmed the IgG2b,kappa subtype previously established. Recloning the H and L chain cDNA information into SV40-based vectors enabled us to obtain expression of functional immunoglobulin upon cotransfection into COS or CHO dhfr- cells. This illustrates that non-lymphoid cells also have the capacity to assemble active immunoglobulins." @default.
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- W2051579237 date "1988-09-01" @default.
- W2051579237 modified "2023-10-03" @default.
- W2051579237 title "Expression in non-lymphoid cells of mouse recombinant immunoglobulindirected against the tumour marker human placental alkaline phosphatase" @default.
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- W2051579237 doi "https://doi.org/10.1111/j.1432-1033.1988.tb14280.x" @default.
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