FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051612014> ?p ?o ?g. }

• W2051612014 endingPage "13" @default.
• W2051612014 startingPage "1" @default.
• W2051612014 abstract "Systematic studies addressing symptoms, signs and temporal aspects of initial bipolar prodrome are reviewed to identify potential clinical targets for early intervention. The databases PsycINFO, PubMed, EMBASE and British Nursing Index were searched for original studies. Eight studies were identified. Irritability and aggressiveness, sleep disturbances, depression and mania symptoms/signs, hyperactivity, anxiety, and mood swings are clusters representing common symptoms and signs of the distal prodrome of bipolar disorder (BD). As time to full BD onset decreases, symptoms of mania and depression seem to increase gradually in strength and prevalence. The specificity of prodromal symptoms and signs appears to be low. Not every person who develops BD experiences a prolonged initial prodrome to the full illness. Current data on the mean duration of the prodrome are contradictory, ranging from 1.8 to 7.3 years. No qualitative studies were found. Because of the scarcity of data, studies that did not explicitly investigate bipolar prodrome were included when thematically relevant. The selected studies are methodologically diverse and the validity of some findings is questionable. Findings must be interpreted cautiously. The initial prodrome of BD is characterized by dysregulation of mood and energy. Because of the apparently low specificity of prodromal symptoms and signs of BD, it is currently neither possible nor advisable to predict the development of BD based solely on early phenomenology. More well-designed in-depth studies, including qualitative ones, are needed to characterize the initial bipolar prodrome." @default.
• W2051612014 created "2016-06-24" @default.
• W2051612014 creator A5013027761 @default.
• W2051612014 creator A5043850750 @default.
• W2051612014 creator A5084225978 @default.
• W2051612014 date "2010-10-01" @default.
• W2051612014 modified "2023-10-15" @default.
• W2051612014 title "Symptoms and signs of the initial prodrome of bipolar disorderA systematic review" @default.
• W2051612014 cites W1493521216 @default.
• W2051612014 cites W1505074765 @default.
• W2051612014 cites W1505408534 @default.
• W2051612014 cites W1605824561 @default.
• W2051612014 cites W1607118314 @default.
• W2051612014 cites W1629717188 @default.
• W2051612014 cites W1741321747 @default.
• W2051612014 cites W1750361104 @default.
• W2051612014 cites W1881281756 @default.
• W2051612014 cites W1913623053 @default.
• W2051612014 cites W1938273588 @default.
• W2051612014 cites W1968910493 @default.
• W2051612014 cites W1971231611 @default.
• W2051612014 cites W1971377155 @default.
• W2051612014 cites W1974109338 @default.
• W2051612014 cites W1975912459 @default.
• W2051612014 cites W1977334056 @default.
• W2051612014 cites W1978353443 @default.
• W2051612014 cites W1979898660 @default.
• W2051612014 cites W1980756087 @default.
• W2051612014 cites W1982931669 @default.
• W2051612014 cites W1983302342 @default.
• W2051612014 cites W1983927699 @default.
• W2051612014 cites W1984576035 @default.
• W2051612014 cites W1985689469 @default.
• W2051612014 cites W1986275520 @default.
• W2051612014 cites W1989448978 @default.
• W2051612014 cites W1990023211 @default.
• W2051612014 cites W1991188405 @default.
• W2051612014 cites W1995051494 @default.
• W2051612014 cites W1995853809 @default.
• W2051612014 cites W1996122356 @default.
• W2051612014 cites W1997983466 @default.
• W2051612014 cites W2000053835 @default.
• W2051612014 cites W2001069382 @default.
• W2051612014 cites W2002772021 @default.
• W2051612014 cites W2007085300 @default.
• W2051612014 cites W2010605833 @default.
• W2051612014 cites W2011709753 @default.
• W2051612014 cites W2012667879 @default.
• W2051612014 cites W2015302726 @default.
• W2051612014 cites W2017223221 @default.
• W2051612014 cites W2017316168 @default.
• W2051612014 cites W2019898719 @default.
• W2051612014 cites W2020362024 @default.
• W2051612014 cites W2020533233 @default.
• W2051612014 cites W2021138997 @default.
• W2051612014 cites W2022085760 @default.
• W2051612014 cites W2024947622 @default.
• W2051612014 cites W2028245040 @default.
• W2051612014 cites W2028894608 @default.
• W2051612014 cites W2029165349 @default.
• W2051612014 cites W2030859524 @default.
• W2051612014 cites W2031343425 @default.
• W2051612014 cites W2032183892 @default.
• W2051612014 cites W2032901459 @default.
• W2051612014 cites W2032990020 @default.
• W2051612014 cites W2035943835 @default.
• W2051612014 cites W2036925825 @default.
• W2051612014 cites W2038722239 @default.
• W2051612014 cites W2040552039 @default.
• W2051612014 cites W2042617382 @default.
• W2051612014 cites W2044136359 @default.
• W2051612014 cites W2044220293 @default.
• W2051612014 cites W2046014297 @default.
• W2051612014 cites W2046655456 @default.
• W2051612014 cites W2049165791 @default.
• W2051612014 cites W2050885757 @default.
• W2051612014 cites W2054170842 @default.
• W2051612014 cites W2054784548 @default.
• W2051612014 cites W2056523594 @default.
• W2051612014 cites W2057023527 @default.
• W2051612014 cites W2060044631 @default.
• W2051612014 cites W2060275148 @default.
• W2051612014 cites W2062281940 @default.
• W2051612014 cites W2062469447 @default.
• W2051612014 cites W2064554173 @default.
• W2051612014 cites W2072090917 @default.
• W2051612014 cites W2074339845 @default.
• W2051612014 cites W2075207083 @default.
• W2051612014 cites W2075422199 @default.
• W2051612014 cites W2075702457 @default.
• W2051612014 cites W2078209715 @default.
• W2051612014 cites W2080350725 @default.
• W2051612014 cites W2081397150 @default.
• W2051612014 cites W2081401977 @default.
• W2051612014 cites W2082287891 @default.
• W2051612014 cites W2082317093 @default.
• W2051612014 cites W2083019926 @default.
• W2051612014 cites W2083915645 @default.

• next