Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051640370> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2051640370 endingPage "321" @default.
- W2051640370 startingPage "317" @default.
- W2051640370 abstract "Porins are highly immunogenic outer membrane proteins of Salmonella. Sera from typhoid patients contained a high level of IgG antibodies directed to porins of Salm. typhi. Since porins are highly conserved proteins, anti-porins antibodies both from typhoid patients and healthy normals reacted with porins from several Gram-negative bacteria. Therefore, in order to improve the specificity of detecting Salm. typhi porins-specific antibodies, an inhibition ELISA was developed using enzyme-conjugated MoAbs (MP1 and MPN4) specific to Salm. typhi porins. Sera from typhoid patients with positive haemoculture (16 out of 17) inhibited the binding of MP1 to porins, thus showing a positive test for typhoid, whereas sera from patients with other Gram-negative bacterial infections (n = 7) and from healthy volunteers (66 out of 67) were found to be negative. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of this assay were 94.1, 98.7, 97.8, 94.1 and 98.7% respectively. The validity of our inhibition ELISA for typhoid was higher than that of the Widal test. The diagnosis of typhoid fever as early as 3 days after the onset of fever, using a single specimen is possible." @default.
- W2051640370 created "2016-06-24" @default.
- W2051640370 creator A5038259876 @default.
- W2051640370 creator A5051505766 @default.
- W2051640370 creator A5087110070 @default.
- W2051640370 date "1993-11-01" @default.
- W2051640370 modified "2023-09-26" @default.
- W2051640370 title "Diagnosis of typhoid fever: detection of <i>Salmonella typhi</i> porins-specific antibodies by inhibition ELISA" @default.
- W2051640370 cites W1479700518 @default.
- W2051640370 cites W1547709209 @default.
- W2051640370 cites W1912233168 @default.
- W2051640370 cites W1976807034 @default.
- W2051640370 cites W1983313772 @default.
- W2051640370 cites W2009361042 @default.
- W2051640370 cites W2034018119 @default.
- W2051640370 cites W2043051147 @default.
- W2051640370 cites W2080726191 @default.
- W2051640370 cites W2091069613 @default.
- W2051640370 cites W2124116610 @default.
- W2051640370 cites W2140244479 @default.
- W2051640370 cites W2171615657 @default.
- W2051640370 cites W2301047814 @default.
- W2051640370 cites W2313715974 @default.
- W2051640370 cites W2316426798 @default.
- W2051640370 cites W2419673938 @default.
- W2051640370 cites W24901846 @default.
- W2051640370 cites W3023372058 @default.
- W2051640370 doi "https://doi.org/10.1111/j.1365-2249.1993.tb03450.x" @default.
- W2051640370 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1534252" @default.
- W2051640370 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8222322" @default.
- W2051640370 hasPublicationYear "1993" @default.
- W2051640370 type Work @default.
- W2051640370 sameAs 2051640370 @default.
- W2051640370 citedByCount "14" @default.
- W2051640370 countsByYear W20516403702013 @default.
- W2051640370 countsByYear W20516403702015 @default.
- W2051640370 countsByYear W20516403702020 @default.
- W2051640370 countsByYear W20516403702021 @default.
- W2051640370 crossrefType "journal-article" @default.
- W2051640370 hasAuthorship W2051640370A5038259876 @default.
- W2051640370 hasAuthorship W2051640370A5051505766 @default.
- W2051640370 hasAuthorship W2051640370A5087110070 @default.
- W2051640370 hasBestOaLocation W20516403701 @default.
- W2051640370 hasConcept C104317684 @default.
- W2051640370 hasConcept C146587185 @default.
- W2051640370 hasConcept C159047783 @default.
- W2051640370 hasConcept C159654299 @default.
- W2051640370 hasConcept C203014093 @default.
- W2051640370 hasConcept C2778837529 @default.
- W2051640370 hasConcept C2781065037 @default.
- W2051640370 hasConcept C2994552716 @default.
- W2051640370 hasConcept C520601542 @default.
- W2051640370 hasConcept C523546767 @default.
- W2051640370 hasConcept C54355233 @default.
- W2051640370 hasConcept C547475151 @default.
- W2051640370 hasConcept C55493867 @default.
- W2051640370 hasConcept C71924100 @default.
- W2051640370 hasConcept C86803240 @default.
- W2051640370 hasConcept C89423630 @default.
- W2051640370 hasConceptScore W2051640370C104317684 @default.
- W2051640370 hasConceptScore W2051640370C146587185 @default.
- W2051640370 hasConceptScore W2051640370C159047783 @default.
- W2051640370 hasConceptScore W2051640370C159654299 @default.
- W2051640370 hasConceptScore W2051640370C203014093 @default.
- W2051640370 hasConceptScore W2051640370C2778837529 @default.
- W2051640370 hasConceptScore W2051640370C2781065037 @default.
- W2051640370 hasConceptScore W2051640370C2994552716 @default.
- W2051640370 hasConceptScore W2051640370C520601542 @default.
- W2051640370 hasConceptScore W2051640370C523546767 @default.
- W2051640370 hasConceptScore W2051640370C54355233 @default.
- W2051640370 hasConceptScore W2051640370C547475151 @default.
- W2051640370 hasConceptScore W2051640370C55493867 @default.
- W2051640370 hasConceptScore W2051640370C71924100 @default.
- W2051640370 hasConceptScore W2051640370C86803240 @default.
- W2051640370 hasConceptScore W2051640370C89423630 @default.
- W2051640370 hasIssue "2" @default.
- W2051640370 hasLocation W20516403701 @default.
- W2051640370 hasLocation W20516403702 @default.
- W2051640370 hasLocation W20516403703 @default.
- W2051640370 hasOpenAccess W2051640370 @default.
- W2051640370 hasPrimaryLocation W20516403701 @default.
- W2051640370 hasRelatedWork W2165577656 @default.
- W2051640370 hasRelatedWork W2319224509 @default.
- W2051640370 hasRelatedWork W2333369221 @default.
- W2051640370 hasRelatedWork W2368553965 @default.
- W2051640370 hasRelatedWork W2412549289 @default.
- W2051640370 hasRelatedWork W2423786332 @default.
- W2051640370 hasRelatedWork W2981566785 @default.
- W2051640370 hasRelatedWork W3193695868 @default.
- W2051640370 hasRelatedWork W4238347664 @default.
- W2051640370 hasRelatedWork W4292380545 @default.
- W2051640370 hasVolume "94" @default.
- W2051640370 isParatext "false" @default.
- W2051640370 isRetracted "false" @default.
- W2051640370 magId "2051640370" @default.
- W2051640370 workType "article" @default.