Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051646189> ?p ?o ?g. }
- W2051646189 endingPage "2873" @default.
- W2051646189 startingPage "2868" @default.
- W2051646189 abstract "Abstract To recover peptides that antigenically and immunogenically mimic the p185 HER2 oncoprotein, we selected the phage‐peptide libraries pVIII‐9aa and pVIII‐9aa. Cys using murine monoclonal antibodies (mAb) MGr2 and MGr6, directed against two distinct epitopes of the p185 HER2 extracellular domain. Phagedisplayed peptides containing consensus amino acid motifs were recovered and shown to compete specifically for mAb binding on tumor cells that overexpress p185 HER2 . The deduced amino acid sequence of the peptides suggests that both epitopes defined by the mAb on p185 HER2 are discontinuous and that hydrophobic interactions are involved in binding with the mAb. A phage clone displaying the GPLDSLFAQ peptide elicited a specific immune response against the p185 HER2 in BALB/c mice, demonstrating that this phage‐displayed peptide represents an immunological equivalent of the MGr2 epitope on p185 HER2 and might be used as a substitute for this oncoprotein in in vitro and in vivo immunological studies." @default.
- W2051646189 created "2016-06-24" @default.
- W2051646189 creator A5005566456 @default.
- W2051646189 creator A5018594390 @default.
- W2051646189 creator A5020540217 @default.
- W2051646189 creator A5074741886 @default.
- W2051646189 creator A5080591515 @default.
- W2051646189 date "1994-11-01" @default.
- W2051646189 modified "2023-09-29" @default.
- W2051646189 title "Antigenic and immunogenic mimicry of the HER2/neu oncoprotein by phage-displayed peptides" @default.
- W2051646189 cites W1487704589 @default.
- W2051646189 cites W1498123779 @default.
- W2051646189 cites W1543240545 @default.
- W2051646189 cites W1591942886 @default.
- W2051646189 cites W1910902924 @default.
- W2051646189 cites W1965030023 @default.
- W2051646189 cites W1973322293 @default.
- W2051646189 cites W1974580327 @default.
- W2051646189 cites W1977958044 @default.
- W2051646189 cites W1994501723 @default.
- W2051646189 cites W1999936841 @default.
- W2051646189 cites W2001604427 @default.
- W2051646189 cites W2001627828 @default.
- W2051646189 cites W2003324907 @default.
- W2051646189 cites W2007256480 @default.
- W2051646189 cites W2016487691 @default.
- W2051646189 cites W2032806769 @default.
- W2051646189 cites W2040608320 @default.
- W2051646189 cites W2046180857 @default.
- W2051646189 cites W2048346523 @default.
- W2051646189 cites W2066386270 @default.
- W2051646189 cites W2072698880 @default.
- W2051646189 cites W2075847417 @default.
- W2051646189 cites W2075879923 @default.
- W2051646189 cites W2082106123 @default.
- W2051646189 cites W2085878255 @default.
- W2051646189 cites W2095156669 @default.
- W2051646189 cites W2117784164 @default.
- W2051646189 cites W2121497936 @default.
- W2051646189 cites W2138270253 @default.
- W2051646189 cites W2159363679 @default.
- W2051646189 cites W2400705724 @default.
- W2051646189 cites W31269597 @default.
- W2051646189 cites W4213384598 @default.
- W2051646189 doi "https://doi.org/10.1002/eji.1830241143" @default.
- W2051646189 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7525309" @default.
- W2051646189 hasPublicationYear "1994" @default.
- W2051646189 type Work @default.
- W2051646189 sameAs 2051646189 @default.
- W2051646189 citedByCount "17" @default.
- W2051646189 countsByYear W20516461892019 @default.
- W2051646189 crossrefType "journal-article" @default.
- W2051646189 hasAuthorship W2051646189A5005566456 @default.
- W2051646189 hasAuthorship W2051646189A5018594390 @default.
- W2051646189 hasAuthorship W2051646189A5020540217 @default.
- W2051646189 hasAuthorship W2051646189A5074741886 @default.
- W2051646189 hasAuthorship W2051646189A5080591515 @default.
- W2051646189 hasConcept C10079403 @default.
- W2051646189 hasConcept C104317684 @default.
- W2051646189 hasConcept C147483822 @default.
- W2051646189 hasConcept C153911025 @default.
- W2051646189 hasConcept C159047783 @default.
- W2051646189 hasConcept C159654299 @default.
- W2051646189 hasConcept C167625842 @default.
- W2051646189 hasConcept C186268636 @default.
- W2051646189 hasConcept C195616568 @default.
- W2051646189 hasConcept C203014093 @default.
- W2051646189 hasConcept C2776441376 @default.
- W2051646189 hasConcept C2776471321 @default.
- W2051646189 hasConcept C2777119779 @default.
- W2051646189 hasConcept C2779281246 @default.
- W2051646189 hasConcept C542903549 @default.
- W2051646189 hasConcept C547475151 @default.
- W2051646189 hasConcept C55493867 @default.
- W2051646189 hasConcept C81089528 @default.
- W2051646189 hasConcept C86803240 @default.
- W2051646189 hasConcept C9365378 @default.
- W2051646189 hasConceptScore W2051646189C10079403 @default.
- W2051646189 hasConceptScore W2051646189C104317684 @default.
- W2051646189 hasConceptScore W2051646189C147483822 @default.
- W2051646189 hasConceptScore W2051646189C153911025 @default.
- W2051646189 hasConceptScore W2051646189C159047783 @default.
- W2051646189 hasConceptScore W2051646189C159654299 @default.
- W2051646189 hasConceptScore W2051646189C167625842 @default.
- W2051646189 hasConceptScore W2051646189C186268636 @default.
- W2051646189 hasConceptScore W2051646189C195616568 @default.
- W2051646189 hasConceptScore W2051646189C203014093 @default.
- W2051646189 hasConceptScore W2051646189C2776441376 @default.
- W2051646189 hasConceptScore W2051646189C2776471321 @default.
- W2051646189 hasConceptScore W2051646189C2777119779 @default.
- W2051646189 hasConceptScore W2051646189C2779281246 @default.
- W2051646189 hasConceptScore W2051646189C542903549 @default.
- W2051646189 hasConceptScore W2051646189C547475151 @default.
- W2051646189 hasConceptScore W2051646189C55493867 @default.
- W2051646189 hasConceptScore W2051646189C81089528 @default.
- W2051646189 hasConceptScore W2051646189C86803240 @default.
- W2051646189 hasConceptScore W2051646189C9365378 @default.
- W2051646189 hasIssue "11" @default.