Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051721714> ?p ?o ?g. }
- W2051721714 endingPage "95" @default.
- W2051721714 startingPage "87" @default.
- W2051721714 abstract "It has recently become apparent that several molecules involved in the control of metabolism also play an important function in the regulation of immune responses. Among those molecules, the adipocyte-derived cytokine leptin has been shown to significantly influence innate and adaptive immune responses both in normal and in pathological conditions. For example, levels of leptin are typically low in infection and high in autoimmunity, both systemically and at the site of inflammation. Moreover, in addition to its long-known effects on the promotion of T helper 1 immune responses and cell-mediated immunity, leptin has more recently been found capable to constrain proliferation of regulatory T cells. As such, leptin represents not only a link between metabolism and immune responses in general but also a pivotal modulator of the magnitude of selected mechanisms of peripheral immunity in relation to body fat mass. We review here the most recent advances on the role of leptin in the control of immune tolerance and critically discuss how strategies aimed at neutralizing the leptin axis could represent innovative tools for the therapy of autoimmune disorders." @default.
- W2051721714 created "2016-06-24" @default.
- W2051721714 creator A5039510130 @default.
- W2051721714 creator A5068046736 @default.
- W2051721714 creator A5084830170 @default.
- W2051721714 date "2007-06-30" @default.
- W2051721714 modified "2023-10-15" @default.
- W2051721714 title "Leptin in autoimmunity: many questions, some answers" @default.
- W2051721714 cites W1525040973 @default.
- W2051721714 cites W1582934864 @default.
- W2051721714 cites W1590709474 @default.
- W2051721714 cites W1590974138 @default.
- W2051721714 cites W1591647694 @default.
- W2051721714 cites W1631449371 @default.
- W2051721714 cites W1644435722 @default.
- W2051721714 cites W1963710754 @default.
- W2051721714 cites W1971203537 @default.
- W2051721714 cites W1972750645 @default.
- W2051721714 cites W1982930336 @default.
- W2051721714 cites W1989758885 @default.
- W2051721714 cites W2004793594 @default.
- W2051721714 cites W2005387606 @default.
- W2051721714 cites W2007267699 @default.
- W2051721714 cites W2011128327 @default.
- W2051721714 cites W2013385151 @default.
- W2051721714 cites W2019926860 @default.
- W2051721714 cites W2020626901 @default.
- W2051721714 cites W2032947001 @default.
- W2051721714 cites W2056305255 @default.
- W2051721714 cites W2059019871 @default.
- W2051721714 cites W2059063316 @default.
- W2051721714 cites W2066528365 @default.
- W2051721714 cites W2068814267 @default.
- W2051721714 cites W2082137006 @default.
- W2051721714 cites W2091085717 @default.
- W2051721714 cites W2096442040 @default.
- W2051721714 cites W2099832244 @default.
- W2051721714 cites W2100937354 @default.
- W2051721714 cites W2103061817 @default.
- W2051721714 cites W2108889338 @default.
- W2051721714 cites W2118213304 @default.
- W2051721714 cites W2120636002 @default.
- W2051721714 cites W2127325185 @default.
- W2051721714 cites W2130064617 @default.
- W2051721714 cites W2164872806 @default.
- W2051721714 cites W2165345254 @default.
- W2051721714 cites W2166756374 @default.
- W2051721714 cites W2170597626 @default.
- W2051721714 cites W2171202452 @default.
- W2051721714 cites W3142542243 @default.
- W2051721714 cites W4205370185 @default.
- W2051721714 cites W4238663920 @default.
- W2051721714 cites W4246400075 @default.
- W2051721714 cites W4322695997 @default.
- W2051721714 doi "https://doi.org/10.1111/j.1399-0039.2007.00886.x" @default.
- W2051721714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17610413" @default.
- W2051721714 hasPublicationYear "2007" @default.
- W2051721714 type Work @default.
- W2051721714 sameAs 2051721714 @default.
- W2051721714 citedByCount "68" @default.
- W2051721714 countsByYear W20517217142013 @default.
- W2051721714 countsByYear W20517217142014 @default.
- W2051721714 countsByYear W20517217142015 @default.
- W2051721714 countsByYear W20517217142016 @default.
- W2051721714 countsByYear W20517217142017 @default.
- W2051721714 countsByYear W20517217142019 @default.
- W2051721714 countsByYear W20517217142020 @default.
- W2051721714 countsByYear W20517217142021 @default.
- W2051721714 countsByYear W20517217142022 @default.
- W2051721714 countsByYear W20517217142023 @default.
- W2051721714 crossrefType "journal-article" @default.
- W2051721714 hasAuthorship W2051721714A5039510130 @default.
- W2051721714 hasAuthorship W2051721714A5068046736 @default.
- W2051721714 hasAuthorship W2051721714A5084830170 @default.
- W2051721714 hasBestOaLocation W20517217141 @default.
- W2051721714 hasConcept C134018914 @default.
- W2051721714 hasConcept C171089720 @default.
- W2051721714 hasConcept C193419808 @default.
- W2051721714 hasConcept C203014093 @default.
- W2051721714 hasConcept C2776175234 @default.
- W2051721714 hasConcept C2776914184 @default.
- W2051721714 hasConcept C2778690821 @default.
- W2051721714 hasConcept C2779341262 @default.
- W2051721714 hasConcept C2780130043 @default.
- W2051721714 hasConcept C2780613262 @default.
- W2051721714 hasConcept C2991704936 @default.
- W2051721714 hasConcept C511355011 @default.
- W2051721714 hasConcept C62231903 @default.
- W2051721714 hasConcept C86803240 @default.
- W2051721714 hasConcept C8891405 @default.
- W2051721714 hasConceptScore W2051721714C134018914 @default.
- W2051721714 hasConceptScore W2051721714C171089720 @default.
- W2051721714 hasConceptScore W2051721714C193419808 @default.
- W2051721714 hasConceptScore W2051721714C203014093 @default.
- W2051721714 hasConceptScore W2051721714C2776175234 @default.
- W2051721714 hasConceptScore W2051721714C2776914184 @default.
- W2051721714 hasConceptScore W2051721714C2778690821 @default.
- W2051721714 hasConceptScore W2051721714C2779341262 @default.