FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2051734319> ?p ?o ?g. }

• W2051734319 abstract "Among 160 patients who were diagnosed as having acute lymphoblastic leukemia (ALL) by French American British (FAB) criteria, 32 patients (20%) expressed myeloid-associated antigens on leukemic blasts (My+ALL). Correlation of immunophenotype with rearrangement of immunoglobulin (Ig) heavy chain and T-cell receptor (TCR) beta chain genes was performed on 73 of these patients (21 were My+ALL). Rearrangements of both Ig and TCR genes (double rearrangements) were detected in 24 patients, including three (19%) of 16 T-lineage ALL. 17 (33%) of 52 B-lineage ALL, and four of five ALL expressing both B and T-cell surface markers. Also a higher incidence of double rearrangements in My+ALL was found as compared with My-ALL (43% vs 29%). This difference was more evident when only B-lineage ALL was considered (50% in My+ patients vs 24% in My- patients). However the difference is not statistically significant yet possibly due to the small number of patients in the study. Further studies on more patients are needed to confirm this. In My-B-lineage ALL, rearrangements of TCR beta chain gene were restricted to certain subgroups (Groups III & IV) of patients who expressed CD10 surface antigens but lacked cytoplasmic Ig. In My+ B-lineage ALL, rearrangements of TCR beta chain gene could be found in various subgroups studied (Groups II through V). Cross-lineage gene rearrangement in My+ALL may involve mechanisms different from those in My-ALL." @default.
• W2051734319 created "2016-06-24" @default.
• W2051734319 creator A5027675518 @default.
• W2051734319 creator A5038807397 @default.
• W2051734319 creator A5059115571 @default.
• W2051734319 creator A5060588529 @default.
• W2051734319 creator A5077634268 @default.
• W2051734319 creator A5078054883 @default.
• W2051734319 creator A5085549661 @default.
• W2051734319 creator A5086609279 @default.
• W2051734319 creator A5089216558 @default.
• W2051734319 date "1991-01-01" @default.
• W2051734319 modified "2023-10-18" @default.
• W2051734319 title "Immunoglobulin and T-cell receptor gene rearrangements in acute lymphoblastic leukemia—A higher incidence of double rearrangements in patients with myeloid antigen expression" @default.
• W2051734319 cites W1508716863 @default.
• W2051734319 cites W1555883714 @default.
• W2051734319 cites W1984724325 @default.
• W2051734319 cites W1993465362 @default.
• W2051734319 cites W2022842992 @default.
• W2051734319 cites W2046840338 @default.
• W2051734319 cites W2054091854 @default.
• W2051734319 cites W2071142530 @default.
• W2051734319 cites W2073504058 @default.
• W2051734319 cites W2076426515 @default.
• W2051734319 cites W2107839276 @default.
• W2051734319 cites W2152171889 @default.
• W2051734319 cites W2269849951 @default.
• W2051734319 cites W2293176221 @default.
• W2051734319 cites W2312581898 @default.
• W2051734319 cites W2328329944 @default.
• W2051734319 cites W2329211716 @default.
• W2051734319 cites W2340094023 @default.
• W2051734319 cites W2342180669 @default.
• W2051734319 cites W2470229754 @default.
• W2051734319 cites W4238121423 @default.
• W2051734319 cites W4251297078 @default.
• W2051734319 cites W63633556 @default.
• W2051734319 cites W71389262 @default.
• W2051734319 doi "https://doi.org/10.1016/0145-2126(91)90088-b" @default.
• W2051734319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1850056" @default.
• W2051734319 hasPublicationYear "1991" @default.
• W2051734319 type Work @default.
• W2051734319 sameAs 2051734319 @default.
• W2051734319 citedByCount "11" @default.
• W2051734319 crossrefType "journal-article" @default.
• W2051734319 hasAuthorship W2051734319A5027675518 @default.
• W2051734319 hasAuthorship W2051734319A5038807397 @default.
• W2051734319 hasAuthorship W2051734319A5059115571 @default.
• W2051734319 hasAuthorship W2051734319A5060588529 @default.
• W2051734319 hasAuthorship W2051734319A5077634268 @default.
• W2051734319 hasAuthorship W2051734319A5078054883 @default.
• W2051734319 hasAuthorship W2051734319A5085549661 @default.
• W2051734319 hasAuthorship W2051734319A5086609279 @default.
• W2051734319 hasAuthorship W2051734319A5089216558 @default.
• W2051734319 hasConcept C104317684 @default.
• W2051734319 hasConcept C147483822 @default.
• W2051734319 hasConcept C153911025 @default.
• W2051734319 hasConcept C159654299 @default.
• W2051734319 hasConcept C19317047 @default.
• W2051734319 hasConcept C196166836 @default.
• W2051734319 hasConcept C203014093 @default.
• W2051734319 hasConcept C2776090121 @default.
• W2051734319 hasConcept C2776817793 @default.
• W2051734319 hasConcept C2779282312 @default.
• W2051734319 hasConcept C2992511266 @default.
• W2051734319 hasConcept C54355233 @default.
• W2051734319 hasConcept C86803240 @default.
• W2051734319 hasConcept C8891405 @default.
• W2051734319 hasConcept C96007430 @default.
• W2051734319 hasConceptScore W2051734319C104317684 @default.
• W2051734319 hasConceptScore W2051734319C147483822 @default.
• W2051734319 hasConceptScore W2051734319C153911025 @default.
• W2051734319 hasConceptScore W2051734319C159654299 @default.
• W2051734319 hasConceptScore W2051734319C19317047 @default.
• W2051734319 hasConceptScore W2051734319C196166836 @default.
• W2051734319 hasConceptScore W2051734319C203014093 @default.
• W2051734319 hasConceptScore W2051734319C2776090121 @default.
• W2051734319 hasConceptScore W2051734319C2776817793 @default.
• W2051734319 hasConceptScore W2051734319C2779282312 @default.
• W2051734319 hasConceptScore W2051734319C2992511266 @default.
• W2051734319 hasConceptScore W2051734319C54355233 @default.
• W2051734319 hasConceptScore W2051734319C86803240 @default.
• W2051734319 hasConceptScore W2051734319C8891405 @default.
• W2051734319 hasConceptScore W2051734319C96007430 @default.
• W2051734319 hasLocation W20517343191 @default.
• W2051734319 hasLocation W20517343192 @default.
• W2051734319 hasOpenAccess W2051734319 @default.
• W2051734319 hasPrimaryLocation W20517343191 @default.
• W2051734319 hasRelatedWork W1243845679 @default.
• W2051734319 hasRelatedWork W1969341073 @default.
• W2051734319 hasRelatedWork W2035545846 @default.
• W2051734319 hasRelatedWork W2051734319 @default.
• W2051734319 hasRelatedWork W206796625 @default.
• W2051734319 hasRelatedWork W2070419208 @default.
• W2051734319 hasRelatedWork W2084920654 @default.
• W2051734319 hasRelatedWork W2353728163 @default.
• W2051734319 hasRelatedWork W2407105665 @default.
• W2051734319 hasRelatedWork W2431259144 @default.
• W2051734319 isParatext "false" @default.
• W2051734319 isRetracted "false" @default.

• next