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• W2051742594 abstract "Xylitol was infused either slowly (500 cc. of 10% solution over 60 minutes) or rapidly (0.33 Gm./Kg. body weight of 50% solution over 2 minutes) into a group of 11 uremic subjects and 10 controls. Similar infusions of glucose were also administered and the plasma xylitol, glucose, phosphate, FFA and serum insulin responses compared. The results have demonstrated that xylitol is well utilized in renal failure. It is rapidly cleared from the blood and the urinary excretion is minimal. It induced a marked fall of plasma phosphate. Although FFA suppressed after the slow infusion, a transient rise was noted when xylitol was administered rapidly. Xylitol stimulated the release of insulin, although the levels attained were less than after glucose. Glucose intolerance was demonstrated in the uremic subjects after its rapid infusion. Although FFA suppressed normally, a delayed and decreased fall of plasma phosphate occurred after the rapid glucose infusion. Xylitol should prove to be a useful source of calories in uremia and in other conditions characterized by carbohydrate intolerance and insulin resistance." @default.
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• W2051742594 date "1970-01-01" @default.
• W2051742594 modified "2023-10-09" @default.
• W2051742594 title "Metabolism of xylitol in healthy subjects and patients with renal disease" @default.
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• W2051742594 doi "https://doi.org/10.1016/0026-0495(70)90114-9" @default.
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