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- W2051809969 abstract "Stokhof AA, Overduin LM, Mol JA, Rijnberk A. Effect of pericardiocentesis on circulating concentrations of atrial natriuretic hormone and arginine vasopressin in dogs with spontaneous pericardial effusion. Eur J Endocrinol 1994;130:357–60. ISSN 0804–4643 Factors regulating the secretion of atrial natriuretic hormone (ANH) and arginine vasopressin (AVP) have not been elucidated fully. In several studies the release of these peptides has been studied by inducing both increased atrial pressure and atrial distension. A few studies employ cardiac tamponade, allowing the effect of atrial pressure and atrial stretch to be studied separately. In eleven dogs with spontaneous cardiac tamponade the effect of pericardiocentesis on circulating concentrations of ANP and AVP was studied. Pericardiocentesis was followed by a prompt rise in (non-elevated) plasma ANH concentrations from 21.6 ± 7.3 to 65.4 ± 17.1 pmol/l (mean ± sem ). The initially slightly elevated AVP concentration of 5.5 ± 1.5 pmol/l declined following pericardiocentesis to 2.1 ± 0.5 pmol/l. In three dogs the systolic arterial pressure was measured indirectly and the central venous pressure was measured with a fluid-filled catheter. Before and after pericardiocentesis arterial pressure readings did not change significantly. Central venous pressure values showed an immediate very steep significant decrease after centesis. It is concluded that ANH release is primarily regulated by stretch and not by atrial pressure, that plasma AVP concentrations are moderately elevated in cardiac tamponade and that in cardiac tamponade pericardiocentesis causes a rapid decline in plasma AVP concentration. Arnold A Stokhof, Department of Clinical Sciences of Companion Animals, Yalelaan 8, 3584 CN Utrecht, The Netherlands" @default.
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- W2051809969 title "Effect of pericardiocentesis on circulating concentrations of atrial natriuretic hormone and arginine vasopressin in dogs with spontaneous pericardial effusion" @default.
- W2051809969 doi "https://doi.org/10.1530/eje.0.1300357" @default.
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