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• W2051819825 abstract "We aim to derive fully autonomous seizure suppression paradigms based on reactive control of neuronal dynamics. A previously derived computational model of seizure generation describing collective degrees of freedom and featuring bistable dynamics is used. A novel technique for real-time control of epileptogenicity is introduced. The reactive control reduces practically all seizures in the model. The study indicates which parameters provide the maximal seizure reduction with minimal intervention. An adaptive scheme is proposed that optimizes the stimulation parameters in nonstationary situations." @default.
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• W2051819825 date "2012-12-30" @default.
• W2051819825 modified "2023-10-05" @default.
• W2051819825 title "REACTIVE CONTROL OF EPILEPTIFORM DISCHARGES IN REALISTIC COMPUTATIONAL NEURONAL MODELS WITH BISTABILITY" @default.
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• W2051819825 doi "https://doi.org/10.1142/s0129065712500323" @default.
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