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- W2051820385 abstract "Interest in compounds that produce a rise in blood pressure was aroused by Oliver and Schafer 1 in 1894, when they found that extracts of the adrenal gland when injected intravenously into animals produced a rise in blood pressure. Intensive study of the gland was begun by Abel, 2 von Furth 3 and Takamine. 4 It remained for Aldrich 5 to demonstrate the true formula for epinephrine, although the value of Abel's contributions is well recognized by the scientific world and it is he who is generally accorded the credit for the first isolation of the principle. This principle he named epinephrin, while von Furth and Takamine, respectively, suggested the names suprarenine and adrenalin. Since the isolation of epinephrine, investigators have attempted to produce more active compounds with more prolonged effectiveness by modifying the structure of the molecule. Although a few changes have resulted in more active preparations, these, in" @default.
- W2051820385 created "2016-06-24" @default.
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- W2051820385 date "1939-01-01" @default.
- W2051820385 modified "2023-10-05" @default.
- W2051820385 title "EPINEPHRINE IN OIL" @default.
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- W2051820385 doi "https://doi.org/10.1001/archinte.1939.00180180129009" @default.
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