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- W2051890488 abstract "Sera positive for antimyolemmal antibodies (AMLAs) from patients with acute biopsy-proven myocarditis exerted a cytotoxic effect on cardiocytes stimulated in vitro. Using an edge-detecting system, contraction amplitude and contraction velocity were altered after the addition of AMLA-positive sera when compared to sera from healthy controls. Antibodies alone did not change the functional parameters. Only the presence of complement and heart-reactive antibodies mediated the detrimental effects. This suggests that a complement-mediated antibody-dependent immune mechanism is operative in human myocarditis." @default.
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- W2051890488 date "1991-08-02" @default.
- W2051890488 modified "2023-10-16" @default.
- W2051890488 title "Impaired myocyte function in vitro incubated with sera from patients with myocarditis" @default.
- W2051890488 doi "https://doi.org/10.1093/eurheartj/12.suppl_d.36" @default.
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