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- W2051917860 abstract "Objective: Factors predicting post-recurrence survival (PRS) in lung adenocarcinoma have not been reported. This study aimed to investigate the prognostic factors of PRS, including the new classification of lung adenocarcinoma proposed by the International Association for the Study of Lung Cancer (IASLC), the American Thoracic Society (ATS), and the European Respiratory Society (ERS), in resected lung adenocarcinoma after recurrence. Methods: The clinicopathological characteristics of 140 patients with recurrence after complete resection of lung adenocarcinoma at Taipei Veterans General Hospital were retrospectively reviewed. The prognostic factors of PRS were analyzed. Results: The pattern of recurrence included local only in 22 (17.1%), distant only in 40 (31.0%), and both local and distant in 84 (51.9%) of patients. The 2- and 4-year PRS were 67.2% and 39.1%, respectively. The most common organ sites of metastasis were the contralateral lung (40.7%), followed by the brain (37.1%) and bone (30.7%). Univariate analysis showed that N2 status (vs. N0 and N1) (P = 0.007), stage III (vs. stage I and II) (P = 0.043), micropapillary/solid predominant pattern group (P = 0.012), liver metastasis (P = 0.033), and no treatment for recurrence (P Conclusions: N2 status, micropapillary/solid predominant pattern group, and no treatment for recurrence predict worse PRS in patients with resected lung adenocarcinoma. The new classification of lung adenocarcinoma had significant impact on PRS. Citation Format: Jung-Jyh Hung, Teh-Ying Chou, Wen-Hu Hsu, Yu-Chung Wu. The impact of IASLC/ATS/ERS classification of lung adenocarcinoma on survival after recurrence in resected adenocarcinoma. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 4667. doi:10.1158/1538-7445.AM2014-4667" @default.
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- W2051917860 date "2014-09-30" @default.
- W2051917860 modified "2023-10-18" @default.
- W2051917860 title "Abstract 4667: The impact of IASLC/ATS/ERS classification of lung adenocarcinoma on survival after recurrence in resected adenocarcinoma" @default.
- W2051917860 doi "https://doi.org/10.1158/1538-7445.am2014-4667" @default.
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