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• W2051949303 abstract "Abstract This paper presented a novel and effective route to prepare oligosaccharide–polypropylene oxide (PPO) surfactant and use thereof to synthesize graft copolymer oligosaccharide–PPO–docetaxel (DTX). The products were characterized by GPC, FTIR and 1 H NMR. Surface tensions of oligosaccharide–PPO surfactants had been investigated using the Du Nouy and steady-state fluorescence methods. The results revealed that the degree of polymerization of the soluble oligosaccharide, which was tailored from cotton cellulose in phosphoric acid medium, was equal to 7; the oligosaccharide–PPO surfactant possessed good surface activity while the adduct number of propylene oxide reached to 20; the DTX was completely dispersed in water medium with oligosaccharide–PPO–DTX micelle and the drug-loading rate reached 32.6%, which showed great potential for clinical application and was worthy of further research." @default.
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• W2051949303 date "2015-01-01" @default.
• W2051949303 modified "2023-09-24" @default.
• W2051949303 title "Preparation of oligosaccharide surfactant based on cotton cellulose and application in hydrophilic modification of docetaxel" @default.
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• W2051949303 doi "https://doi.org/10.1016/j.colcom.2015.04.002" @default.
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