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- W2051986521 abstract "Abstract A green pigment which appeared in patients having subacute myelo-opticoneuropathy (SMON) was identified as ferric chelate of clioquinol; moreover, a large quantity of crystalline clioquinol was found in urine of a SMON patient. A sensitive method for gas chromatographic determination of unconjugated clioquinol has been developed and applied to specimens from SMON patients. About 10 μg of clioquinol was found in 1 ml of serum after a 1-month suspension of the drug, and about 0.1 μg was found per g of sciatic nerve after a 9-month suspension. Based on these results, a toxicity mechanism is discussed." @default.
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- W2051986521 date "1973-08-01" @default.
- W2051986521 modified "2023-10-01" @default.
- W2051986521 title "Identification of green pigment and analysis of clioquinol in specimens from patients with subacute myelo-optico-neuropathy" @default.
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- W2051986521 doi "https://doi.org/10.1016/0009-8981(73)90052-1" @default.
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