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• W2052012247 abstract "Sera from patients with asthma, chronic bronchitis, bronchiectasis, cystic fibrosis, pulmonary tuberculosis, bronchial carcinoma, or chronic klebsiella pneumonia, and from healthy controls were examined for precipitating antibody to enterobacteria by agar-gel diffusion. Precipitins believed to be specific to the Enterobacteriaceæ, but not to any member species in particular, and demonstrable by immunoelectrophoresis, were found in some patients with chronic destructive bronchial conditions such as bronchiectasis and cystic fibrosis, and also in those with chronic klebsiella pneumonia, but not in chronic bronchitics. Usually, the presence of such antibody in serum was associated with that of a mucoid strain of klebsiella in the sputum, but only when the sputum was purulent. Mucoid Klebsiella ozœnœ of capsular type 4 seemed to have a specific role as a cause of secondary infection in established chronic destructive disorders of the bronchi. Non-mucoid klebsiellæ and enterobacteria of genera other than Klebsiella (e.g., Escherichia coli or Proteus spp.) occurred in sputum without any association with pus, or with enterobacteria-specific antibody in the serum, and it is concluded that they are not pathogens in chronic bronchial disorders." @default.
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• W2052012247 date "1968-02-01" @default.
• W2052012247 modified "2023-10-11" @default.
• W2052012247 title "PRECIPITINS TO KLEBSIELLA AND OTHER ENTEROBACTERIA IN THE SERUM OF PATIENTS WITH CHRONIC RESPIRATORY DISORDERS" @default.
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• W2052012247 doi "https://doi.org/10.1016/s0140-6736(68)91353-6" @default.
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