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- W2052027060 abstract "638 The effects of the antihypertensive agent Losartan (LO) on acute exercise performance was assessed in six sedentary hypertensive women [age: 41 ± 6.0 yr (SD)]. Subjects completed a preliminary incremental (30 Watt·2 min-1) cycle ergometer test for VO2pk. In a double-blinded crossover design, subjects were randomized to 7 d of (LO) 50 mg or placebo(PL) every morning. Subjects received the final dose 2.5 hr prior to the exercise trials. Circulatory and respiratory measurements were obtained at rest and at a fixed cycling load equivalent to 45% of peak VO2pk. Following collection of the submaximal data, they shifted to an incremental loading at 30 Watt·2 min-1 progression until fatigue. Circulatory responses to the submaximal steady-state exercise after 7 d of PL and LO treatment were (mean ± SEM): TableTableIn conclusion, Losartan favorably reduced BP and TPRI without altering respiratory or perceptual indicators of demand in moderate exercise by hypertensive women." @default.
- W2052027060 created "2016-06-24" @default.
- W2052027060 creator A5028192940 @default.
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- W2052027060 creator A5057613855 @default.
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- W2052027060 date "1998-05-01" @default.
- W2052027060 modified "2023-09-26" @default.
- W2052027060 title "EFFECTS OF THE ANGIOTENSIN II ANTAGONIST, LOSARTAN ON CIRCULO-RESPIRATORY RESPONSES TO SUBMAXIMAL EXERCISE IN HYPERTENSIVE WOMEN" @default.
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