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• W2052053632 abstract "A didemnin B analog containing a Tic (1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid) as a conformationally restrained replacement for tyrosine has been synthesized and shown to have comparable potency as a protein biosynthesis inhibitor. Synthetic highlights include an oxidation of an alcohol to an acid in the presence of the sensitive Tic heterocycle and a modified Schmidt-type one-pot macrocyclization." @default.
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• W2052053632 date "1998-12-01" @default.
• W2052053632 modified "2023-10-10" @default.
• W2052053632 title "Synthesis and biological activity of [Tic5] didemnin B" @default.
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• W2052053632 doi "https://doi.org/10.1016/s0960-894x(98)00662-3" @default.
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