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- W2052070514 abstract "We evaluated the prognostic role of 18FDG-PET performed before ASCT in patients affected by lymphoma who underwent high-dose chemotherapy followed by ASCT as first-line treatment for high-risk disease or as second-line or more for relapsed or refractory disease. We retrospectively analyzed 53 consecutive patients, 14 with Hodgkin Lymphoma (HL) and 39 with non-Hodgkin Lymphoma (NHL), treated between February 1999 and October 2006 at our institution, who had a pre-ASCT FDG-PET (pPET) evaluation. Median age was 45 years (range: 18 – 69). After a median follow-up of 31 months (range: 8 – 91), 7 out of 16 pPET+ patients and 10 out of 37 pPET− patients experienced lymphoma relapse. The 5-year OS is 90% and 55% (p = 0.01) in patients with negative and positive pPET, respectively. In conclusion, a positive pPET indicates a poorer outcome after ASCT with respect to a negative pPET; this subset of patients should be considered candidate to more intensive or investigational approaches." @default.
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- W2052070514 date "2008-01-01" @default.
- W2052070514 modified "2023-09-27" @default.
- W2052070514 title "Pre-transplant<sup>18</sup>FDG-PET predicts outcome in lymphoma patients treated with high-dose sequential chemotherapy followed by autologous stem cell transplantation" @default.
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- W2052070514 doi "https://doi.org/10.1080/10428190701885545" @default.
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