Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052085244> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2052085244 endingPage "166" @default.
- W2052085244 startingPage "161" @default.
- W2052085244 abstract "Ezetimibe is a drug that selectively inhibits cholesterol absorption and further reduces LDL-C when used in addition to statins. The ENHANCE trial is a randomized study aimed at studying the effect of ezetimibe on top of simvastatin versus simvastatin on carotid intima-media thickness in 720 patients with heterozygous familial hypercholesterolemia. Despite achieving a significant differential reduction in LDL-C, no regression in carotid intima-media thickness was observed at the end of the 2-year follow-up period. Among the many reasons for these negative results, the relatively normal carotid intima-media thickness of the patients at baseline and the change in characteristics of the plaque without changes in plaque volume might be the most likely explanations. Nevertheless, the results of the ongoing outcome trials with ezetimibe are needed to know for certain the effect of ezetimibe on clinical outcomes." @default.
- W2052085244 created "2016-06-24" @default.
- W2052085244 creator A5051369406 @default.
- W2052085244 date "2010-04-01" @default.
- W2052085244 modified "2023-09-27" @default.
- W2052085244 title "The ENHANCE trial: analysis and clinical significance" @default.
- W2052085244 cites W1561566764 @default.
- W2052085244 cites W1968240228 @default.
- W2052085244 cites W1985932775 @default.
- W2052085244 cites W2004936310 @default.
- W2052085244 cites W2023649310 @default.
- W2052085244 cites W2051877954 @default.
- W2052085244 cites W2080945076 @default.
- W2052085244 cites W2088126428 @default.
- W2052085244 cites W2101267898 @default.
- W2052085244 cites W2101969945 @default.
- W2052085244 cites W2104463342 @default.
- W2052085244 cites W2111385165 @default.
- W2052085244 cites W2116416944 @default.
- W2052085244 cites W2120289695 @default.
- W2052085244 cites W2122975632 @default.
- W2052085244 cites W2123002906 @default.
- W2052085244 cites W2132162389 @default.
- W2052085244 cites W2136706160 @default.
- W2052085244 cites W2136964217 @default.
- W2052085244 cites W2137983259 @default.
- W2052085244 cites W2142283630 @default.
- W2052085244 cites W2146228563 @default.
- W2052085244 cites W2147346175 @default.
- W2052085244 cites W2150799450 @default.
- W2052085244 cites W2161453510 @default.
- W2052085244 cites W2167045683 @default.
- W2052085244 cites W2170452015 @default.
- W2052085244 doi "https://doi.org/10.2217/clp.10.14" @default.
- W2052085244 hasPublicationYear "2010" @default.
- W2052085244 type Work @default.
- W2052085244 sameAs 2052085244 @default.
- W2052085244 citedByCount "4" @default.
- W2052085244 countsByYear W20520852442012 @default.
- W2052085244 countsByYear W20520852442016 @default.
- W2052085244 crossrefType "journal-article" @default.
- W2052085244 hasAuthorship W2052085244A5051369406 @default.
- W2052085244 hasBestOaLocation W20520852441 @default.
- W2052085244 hasConcept C126322002 @default.
- W2052085244 hasConcept C164705383 @default.
- W2052085244 hasConcept C168563851 @default.
- W2052085244 hasConcept C2776329913 @default.
- W2052085244 hasConcept C2776839432 @default.
- W2052085244 hasConcept C2778163477 @default.
- W2052085244 hasConcept C2778657065 @default.
- W2052085244 hasConcept C2779120738 @default.
- W2052085244 hasConcept C2779339615 @default.
- W2052085244 hasConcept C2987047532 @default.
- W2052085244 hasConcept C3019882007 @default.
- W2052085244 hasConcept C535046627 @default.
- W2052085244 hasConcept C71924100 @default.
- W2052085244 hasConcept C90924648 @default.
- W2052085244 hasConceptScore W2052085244C126322002 @default.
- W2052085244 hasConceptScore W2052085244C164705383 @default.
- W2052085244 hasConceptScore W2052085244C168563851 @default.
- W2052085244 hasConceptScore W2052085244C2776329913 @default.
- W2052085244 hasConceptScore W2052085244C2776839432 @default.
- W2052085244 hasConceptScore W2052085244C2778163477 @default.
- W2052085244 hasConceptScore W2052085244C2778657065 @default.
- W2052085244 hasConceptScore W2052085244C2779120738 @default.
- W2052085244 hasConceptScore W2052085244C2779339615 @default.
- W2052085244 hasConceptScore W2052085244C2987047532 @default.
- W2052085244 hasConceptScore W2052085244C3019882007 @default.
- W2052085244 hasConceptScore W2052085244C535046627 @default.
- W2052085244 hasConceptScore W2052085244C71924100 @default.
- W2052085244 hasConceptScore W2052085244C90924648 @default.
- W2052085244 hasIssue "2" @default.
- W2052085244 hasLocation W20520852441 @default.
- W2052085244 hasOpenAccess W2052085244 @default.
- W2052085244 hasPrimaryLocation W20520852441 @default.
- W2052085244 hasRelatedWork W1980695468 @default.
- W2052085244 hasRelatedWork W2014051043 @default.
- W2052085244 hasRelatedWork W2079436645 @default.
- W2052085244 hasRelatedWork W2097281569 @default.
- W2052085244 hasRelatedWork W2120289695 @default.
- W2052085244 hasRelatedWork W2168876694 @default.
- W2052085244 hasRelatedWork W2345942136 @default.
- W2052085244 hasRelatedWork W2411314743 @default.
- W2052085244 hasRelatedWork W2615273108 @default.
- W2052085244 hasRelatedWork W45701024 @default.
- W2052085244 hasVolume "5" @default.
- W2052085244 isParatext "false" @default.
- W2052085244 isRetracted "false" @default.
- W2052085244 magId "2052085244" @default.
- W2052085244 workType "article" @default.