FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052156429> ?p ?o ?g. }

• W2052156429 endingPage "157" @default.
• W2052156429 startingPage "153" @default.
• W2052156429 abstract "Vagal nerve stimulation (VNS) is a therapeutic add-on treatment for patients with pharmaco-resistant epilepsy. The mechanism of action is still largely unknown. Previous studies have shown that brain network topology during the inter-ictal period in epileptic patients deviates from normal configuration. In the present paper, we investigate the relationship between clinical improvement induced by VNS and alterations in brain network topology. We hypothesize that, as a consequence of the VNS add-on treatment, functional brain network architecture shifts back toward a more efficient configuration in patients responding to VNS. Electroencephalographic (EEG) recordings from ten patients affected by pharmaco-resistant epilepsy were analyzed in the classical EEG frequency bands. The phase lag index (PLI) was used to estimate functional connectivity between EEG channels and the minimum spanning tree (MST) was computed in order to characterize VNS-induced alterations in network topology in a bias-free way. Our results revealed a clear network re-organization, in terms of MST modification, toward a more integrated architecture in patients responding to the VNS. In particular, the results show a significant interaction effect between benefit from VNS (responders/non-responders) and condition (pre/post VNS implantation) in the theta band. This finding suggests that the positive effect induced by VNS add-on treatment in epileptic patients is related to a clear network re-organization and that this network modification can reveal the long debated mechanism of action of VNS. Therefore, MST analysis could be useful in evaluating and monitoring the efficacy of VNS add-on treatment potentially in both epilepsy and psychiatric diseases." @default.
• W2052156429 created "2016-06-24" @default.
• W2052156429 creator A5000007331 @default.
• W2052156429 creator A5001827320 @default.
• W2052156429 creator A5010822338 @default.
• W2052156429 creator A5016639346 @default.
• W2052156429 creator A5040228633 @default.
• W2052156429 creator A5046921350 @default.
• W2052156429 creator A5057855392 @default.
• W2052156429 creator A5063161114 @default.
• W2052156429 creator A5087722530 @default.
• W2052156429 date "2014-09-01" @default.
• W2052156429 modified "2023-10-14" @default.
• W2052156429 title "The re-organization of functional brain networks in pharmaco-resistant epileptic patients who respond to VNS" @default.
• W2052156429 cites W1560895878 @default.
• W2052156429 cites W1866535452 @default.
• W2052156429 cites W1965680834 @default.
• W2052156429 cites W1971482087 @default.
• W2052156429 cites W1973616821 @default.
• W2052156429 cites W1978483218 @default.
• W2052156429 cites W1979426401 @default.
• W2052156429 cites W1985932255 @default.
• W2052156429 cites W1991362940 @default.
• W2052156429 cites W2009409311 @default.
• W2052156429 cites W2011961540 @default.
• W2052156429 cites W2016454497 @default.
• W2052156429 cites W2021947606 @default.
• W2052156429 cites W2022305238 @default.
• W2052156429 cites W2026355610 @default.
• W2052156429 cites W2026384313 @default.
• W2052156429 cites W2030485012 @default.
• W2052156429 cites W2035623830 @default.
• W2052156429 cites W2041570400 @default.
• W2052156429 cites W2055105545 @default.
• W2052156429 cites W2061950760 @default.
• W2052156429 cites W2073295462 @default.
• W2052156429 cites W2077382439 @default.
• W2052156429 cites W2081349923 @default.
• W2052156429 cites W2083570561 @default.
• W2052156429 cites W2085756185 @default.
• W2052156429 cites W2093729275 @default.
• W2052156429 cites W2094292488 @default.
• W2052156429 cites W2095689927 @default.
• W2052156429 cites W2109582949 @default.
• W2052156429 cites W2124784672 @default.
• W2052156429 cites W2127888717 @default.
• W2052156429 cites W2136795687 @default.
• W2052156429 cites W2140848476 @default.
• W2052156429 cites W2144528160 @default.
• W2052156429 cites W2148155494 @default.
• W2052156429 cites W2148479386 @default.
• W2052156429 cites W2153436764 @default.
• W2052156429 cites W2154997432 @default.
• W2052156429 cites W2160923999 @default.
• W2052156429 cites W2166148649 @default.
• W2052156429 cites W2168690225 @default.
• W2052156429 cites W2171871508 @default.
• W2052156429 doi "https://doi.org/10.1016/j.neulet.2014.08.010" @default.
• W2052156429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25123446" @default.
• W2052156429 hasPublicationYear "2014" @default.
• W2052156429 type Work @default.
• W2052156429 sameAs 2052156429 @default.
• W2052156429 citedByCount "43" @default.
• W2052156429 countsByYear W20521564292015 @default.
• W2052156429 countsByYear W20521564292016 @default.
• W2052156429 countsByYear W20521564292017 @default.
• W2052156429 countsByYear W20521564292018 @default.
• W2052156429 countsByYear W20521564292019 @default.
• W2052156429 countsByYear W20521564292020 @default.
• W2052156429 countsByYear W20521564292021 @default.
• W2052156429 countsByYear W20521564292022 @default.
• W2052156429 countsByYear W20521564292023 @default.
• W2052156429 crossrefType "journal-article" @default.
• W2052156429 hasAuthorship W2052156429A5000007331 @default.
• W2052156429 hasAuthorship W2052156429A5001827320 @default.
• W2052156429 hasAuthorship W2052156429A5010822338 @default.
• W2052156429 hasAuthorship W2052156429A5016639346 @default.
• W2052156429 hasAuthorship W2052156429A5040228633 @default.
• W2052156429 hasAuthorship W2052156429A5046921350 @default.
• W2052156429 hasAuthorship W2052156429A5057855392 @default.
• W2052156429 hasAuthorship W2052156429A5063161114 @default.
• W2052156429 hasAuthorship W2052156429A5087722530 @default.
• W2052156429 hasConcept C111472728 @default.
• W2052156429 hasConcept C114614502 @default.
• W2052156429 hasConcept C138885662 @default.
• W2052156429 hasConcept C15744967 @default.
• W2052156429 hasConcept C169760540 @default.
• W2052156429 hasConcept C17755696 @default.
• W2052156429 hasConcept C184720557 @default.
• W2052156429 hasConcept C24998067 @default.
• W2052156429 hasConcept C2778186239 @default.
• W2052156429 hasConcept C2780087125 @default.
• W2052156429 hasConcept C2781404750 @default.
• W2052156429 hasConcept C3018011982 @default.
• W2052156429 hasConcept C33923547 @default.
• W2052156429 hasConcept C41008148 @default.
• W2052156429 hasConcept C522805319 @default.
• W2052156429 hasConcept C89611455 @default.

• next