FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052166953> ?p ?o ?g. }

• W2052166953 endingPage "5961" @default.
• W2052166953 startingPage "5950" @default.
• W2052166953 abstract "To obtain a better understanding of how hippocampal neurons selectively target proteins to axons, we assessed whether any of the large cytoplasmic regions of neuronal sodium channel Na(v)1.2 contain sufficient information for axonal compartmentalization. We show that addition of the cytoplasmic C-terminal region of Na(v)1.2 restricted the distribution of a dendritic-axonal reporter protein to axons. The analysis of mutants revealed that a critical segment of nine amino acids encompassing a di-leucine-based motif mediates axonal compartmentalization of chimera. In addition, the Na(v)1.2 C-terminus is recognized by the clathrin endocytic pathway both in non-neuronal cells and the somatodendritic domain of hippocampal neurons. The mutation of the di-leucine motif located within the nine amino acid sequence to alanines resulted in the loss of chimera compartmentalization in axons and of internalization. These data suggest that selective elimination by endocytosis in dendrites may account for the compartmentalized distribution of some proteins in axons." @default.
• W2052166953 created "2016-06-24" @default.
• W2052166953 creator A5087874511 @default.
• W2052166953 date "2001-11-01" @default.
• W2052166953 modified "2023-09-25" @default.
• W2052166953 title "Identification of an axonal determinant in the C-terminus of the sodium channel Nav1.2" @default.
• W2052166953 cites W1494525315 @default.
• W2052166953 cites W1553759318 @default.
• W2052166953 cites W1584917605 @default.
• W2052166953 cites W1848481221 @default.
• W2052166953 cites W1920889222 @default.
• W2052166953 cites W1946755838 @default.
• W2052166953 cites W1973010184 @default.
• W2052166953 cites W1980548298 @default.
• W2052166953 cites W1983187084 @default.
• W2052166953 cites W1983396112 @default.
• W2052166953 cites W1995136282 @default.
• W2052166953 cites W2015285707 @default.
• W2052166953 cites W2028656676 @default.
• W2052166953 cites W2030610882 @default.
• W2052166953 cites W2038974499 @default.
• W2052166953 cites W2045554245 @default.
• W2052166953 cites W2048773003 @default.
• W2052166953 cites W2057426891 @default.
• W2052166953 cites W2060705097 @default.
• W2052166953 cites W2076135679 @default.
• W2052166953 cites W2080633827 @default.
• W2052166953 cites W2083184552 @default.
• W2052166953 cites W2084886317 @default.
• W2052166953 cites W2086617915 @default.
• W2052166953 cites W2096501276 @default.
• W2052166953 cites W2107517282 @default.
• W2052166953 cites W2110728570 @default.
• W2052166953 cites W2114911095 @default.
• W2052166953 cites W2117107937 @default.
• W2052166953 cites W2131803903 @default.
• W2052166953 cites W2134344512 @default.
• W2052166953 cites W2142498139 @default.
• W2052166953 cites W2148188096 @default.
• W2052166953 cites W2150796852 @default.
• W2052166953 cites W2152709230 @default.
• W2052166953 cites W2158408960 @default.
• W2052166953 cites W2161396884 @default.
• W2052166953 cites W2167991458 @default.
• W2052166953 cites W308270796 @default.
• W2052166953 cites W73391000 @default.
• W2052166953 doi "https://doi.org/10.1093/emboj/20.21.5950" @default.
• W2052166953 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/125703" @default.
• W2052166953 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11689435" @default.
• W2052166953 hasPublicationYear "2001" @default.
• W2052166953 type Work @default.
• W2052166953 sameAs 2052166953 @default.
• W2052166953 citedByCount "133" @default.
• W2052166953 countsByYear W20521669532012 @default.
• W2052166953 countsByYear W20521669532013 @default.
• W2052166953 countsByYear W20521669532014 @default.
• W2052166953 countsByYear W20521669532015 @default.
• W2052166953 countsByYear W20521669532016 @default.
• W2052166953 countsByYear W20521669532017 @default.
• W2052166953 countsByYear W20521669532018 @default.
• W2052166953 countsByYear W20521669532019 @default.
• W2052166953 countsByYear W20521669532020 @default.
• W2052166953 countsByYear W20521669532021 @default.
• W2052166953 countsByYear W20521669532022 @default.
• W2052166953 countsByYear W20521669532023 @default.
• W2052166953 crossrefType "journal-article" @default.
• W2052166953 hasAuthorship W2052166953A5087874511 @default.
• W2052166953 hasBestOaLocation W20521669532 @default.
• W2052166953 hasConcept C104317684 @default.
• W2052166953 hasConcept C110455231 @default.
• W2052166953 hasConcept C148762608 @default.
• W2052166953 hasConcept C169760540 @default.
• W2052166953 hasConcept C170493617 @default.
• W2052166953 hasConcept C178790620 @default.
• W2052166953 hasConcept C181199279 @default.
• W2052166953 hasConcept C185592680 @default.
• W2052166953 hasConcept C190062978 @default.
• W2052166953 hasConcept C2776165026 @default.
• W2052166953 hasConcept C2778794669 @default.
• W2052166953 hasConcept C28005876 @default.
• W2052166953 hasConcept C30278631 @default.
• W2052166953 hasConcept C50952357 @default.
• W2052166953 hasConcept C515207424 @default.
• W2052166953 hasConcept C537181965 @default.
• W2052166953 hasConcept C55493867 @default.
• W2052166953 hasConcept C57711820 @default.
• W2052166953 hasConcept C79747257 @default.
• W2052166953 hasConcept C86803240 @default.
• W2052166953 hasConcept C95444343 @default.
• W2052166953 hasConceptScore W2052166953C104317684 @default.
• W2052166953 hasConceptScore W2052166953C110455231 @default.
• W2052166953 hasConceptScore W2052166953C148762608 @default.
• W2052166953 hasConceptScore W2052166953C169760540 @default.
• W2052166953 hasConceptScore W2052166953C170493617 @default.
• W2052166953 hasConceptScore W2052166953C178790620 @default.
• W2052166953 hasConceptScore W2052166953C181199279 @default.
• W2052166953 hasConceptScore W2052166953C185592680 @default.
• W2052166953 hasConceptScore W2052166953C190062978 @default.

• next