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- W2052205730 abstract "We addressed the question of whether (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801) and dl-(E)2-amino-4-methyl-5-phosiphono-3-pentenoic acid (CGP37849), a non-competitive and a competitive N-methyl-d-aspartate (NMDA) receptor antagonist, respectively, are able to block morphine-induced conditioned place preference (CPP). MK-801 alone (0.1 mg/kg) produced neither a place preference nor a place aversion, but was able to completely block morphine-induced CPP. CGP37849 alone (10 mg/kg) produced a small but significant CPP, and was able to significantly attenuate morphine-induced CPP These results cannot be due to simple additive effects of drug actions, but suggest that NMDA receptors play a complex role in the development of morphine CPP." @default.
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- W2052205730 date "1995-06-01" @default.
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- W2052205730 title "N-Methyl-d-aspartic acid-receptor antagonists block morphine-induced conditioned place preference in rats" @default.
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- W2052205730 doi "https://doi.org/10.1016/0304-3940(95)11662-g" @default.
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