FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052207845> ?p ?o ?g. }

• W2052207845 endingPage "144" @default.
• W2052207845 startingPage "137" @default.
• W2052207845 abstract "The depolarization-evoked release of gamma-aminobutyric acid (GABA) and its modulation mediated by autoreceptors were studied in superfused synaptosomes prepared from the pars compacta and from the pars reticulata of the rat substantia nigra. The release of [3H]GABA evoked by 9 mM KCl was almost totally calcium-dependent in both nigral subregions. In the presence of SK&F 89976A (N-(4,4-diphenyl-3-butenyl)nipecotic acid), a GABA uptake inhibitor added to minimize carrier-mediated homoexchange, GABA (0.3-10 microM) inhibited, in a concentration-dependent way, the K(+)-evoked overflow of [3H]GABA from both pars compacta and pars reticulata synaptosomes. Similarly to GABA, (-)-baclofen (0.3-10 microM) reduced the [3H]GABA overflow, being roughly equipotent to GABA in both nigral subregions. The (+) enantiomer of baclofen was ineffective. The overflow of [3H]GABA was not consistently affected by muscimol in either the pars compacta or the pars reticulata. The effects of GABA were bicuculline- and picrotoxin-insensitive. However, the inhibition by GABA of the [3H]GABA overflow was antagonized by phaclofen. It is concluded that (a) GABA autoreceptors are sited on GABAergic nerve endings in both the pars compacta and pars reticulata of the rat substantia nigra; (b) these autoreceptors belong to the GABAB type." @default.
• W2052207845 created "2016-06-24" @default.
• W2052207845 creator A5015779278 @default.
• W2052207845 creator A5048232498 @default.
• W2052207845 creator A5058725409 @default.
• W2052207845 date "1990-01-01" @default.
• W2052207845 modified "2023-09-23" @default.
• W2052207845 title "GABA terminal autoreceptors in the pars compacta and in the pars reticulata of the rat substantia nigra are GABAB" @default.
• W2052207845 cites W1964258288 @default.
• W2052207845 cites W1969223916 @default.
• W2052207845 cites W1972326540 @default.
• W2052207845 cites W1985893094 @default.
• W2052207845 cites W1998107657 @default.
• W2052207845 cites W1998407973 @default.
• W2052207845 cites W2009396705 @default.
• W2052207845 cites W2025437164 @default.
• W2052207845 cites W2036236793 @default.
• W2052207845 cites W2042717783 @default.
• W2052207845 cites W2050750445 @default.
• W2052207845 cites W2055732887 @default.
• W2052207845 cites W2059172718 @default.
• W2052207845 cites W2061885795 @default.
• W2052207845 cites W2081194738 @default.
• W2052207845 cites W2081301520 @default.
• W2052207845 cites W2093458662 @default.
• W2052207845 cites W2095250892 @default.
• W2052207845 cites W4293247451 @default.
• W2052207845 doi "https://doi.org/10.1016/0014-2999(90)90224-t" @default.
• W2052207845 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2155793" @default.
• W2052207845 hasPublicationYear "1990" @default.
• W2052207845 type Work @default.
• W2052207845 sameAs 2052207845 @default.
• W2052207845 citedByCount "46" @default.
• W2052207845 countsByYear W20522078452016 @default.
• W2052207845 countsByYear W20522078452017 @default.
• W2052207845 countsByYear W20522078452021 @default.
• W2052207845 crossrefType "journal-article" @default.
• W2052207845 hasAuthorship W2052207845A5015779278 @default.
• W2052207845 hasAuthorship W2052207845A5048232498 @default.
• W2052207845 hasAuthorship W2052207845A5058725409 @default.
• W2052207845 hasConcept C101027131 @default.
• W2052207845 hasConcept C126322002 @default.
• W2052207845 hasConcept C134018914 @default.
• W2052207845 hasConcept C137183658 @default.
• W2052207845 hasConcept C168258287 @default.
• W2052207845 hasConcept C169760540 @default.
• W2052207845 hasConcept C170493617 @default.
• W2052207845 hasConcept C17077164 @default.
• W2052207845 hasConcept C185592680 @default.
• W2052207845 hasConcept C2776055257 @default.
• W2052207845 hasConcept C2776219046 @default.
• W2052207845 hasConcept C2776773494 @default.
• W2052207845 hasConcept C2777186548 @default.
• W2052207845 hasConcept C2778938600 @default.
• W2052207845 hasConcept C2779177108 @default.
• W2052207845 hasConcept C2779188335 @default.
• W2052207845 hasConcept C2779324764 @default.
• W2052207845 hasConcept C2780763569 @default.
• W2052207845 hasConcept C2780938664 @default.
• W2052207845 hasConcept C2781201050 @default.
• W2052207845 hasConcept C513476851 @default.
• W2052207845 hasConcept C529278444 @default.
• W2052207845 hasConcept C55493867 @default.
• W2052207845 hasConcept C71924100 @default.
• W2052207845 hasConcept C8439214 @default.
• W2052207845 hasConcept C86803240 @default.
• W2052207845 hasConceptScore W2052207845C101027131 @default.
• W2052207845 hasConceptScore W2052207845C126322002 @default.
• W2052207845 hasConceptScore W2052207845C134018914 @default.
• W2052207845 hasConceptScore W2052207845C137183658 @default.
• W2052207845 hasConceptScore W2052207845C168258287 @default.
• W2052207845 hasConceptScore W2052207845C169760540 @default.
• W2052207845 hasConceptScore W2052207845C170493617 @default.
• W2052207845 hasConceptScore W2052207845C17077164 @default.
• W2052207845 hasConceptScore W2052207845C185592680 @default.
• W2052207845 hasConceptScore W2052207845C2776055257 @default.
• W2052207845 hasConceptScore W2052207845C2776219046 @default.
• W2052207845 hasConceptScore W2052207845C2776773494 @default.
• W2052207845 hasConceptScore W2052207845C2777186548 @default.
• W2052207845 hasConceptScore W2052207845C2778938600 @default.
• W2052207845 hasConceptScore W2052207845C2779177108 @default.
• W2052207845 hasConceptScore W2052207845C2779188335 @default.
• W2052207845 hasConceptScore W2052207845C2779324764 @default.
• W2052207845 hasConceptScore W2052207845C2780763569 @default.
• W2052207845 hasConceptScore W2052207845C2780938664 @default.
• W2052207845 hasConceptScore W2052207845C2781201050 @default.
• W2052207845 hasConceptScore W2052207845C513476851 @default.
• W2052207845 hasConceptScore W2052207845C529278444 @default.
• W2052207845 hasConceptScore W2052207845C55493867 @default.
• W2052207845 hasConceptScore W2052207845C71924100 @default.
• W2052207845 hasConceptScore W2052207845C8439214 @default.
• W2052207845 hasConceptScore W2052207845C86803240 @default.
• W2052207845 hasIssue "2" @default.
• W2052207845 hasLocation W20522078451 @default.
• W2052207845 hasLocation W20522078452 @default.
• W2052207845 hasOpenAccess W2052207845 @default.
• W2052207845 hasPrimaryLocation W20522078451 @default.
• W2052207845 hasRelatedWork W1985893094 @default.

• next