Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052242367> ?p ?o ?g. }
- W2052242367 endingPage "1081" @default.
- W2052242367 startingPage "1074" @default.
- W2052242367 abstract "Iron is essential for maintaining cellular metabolism of most organisms. Iron chelators such as desferrioxamine have been used clinically in the treatment of iron overload diseases. In the present study, we used human colon adenocarcinoma cells as a proliferating cell model to validate that desferrioxamine inhibits cell proliferation and induces apoptosis. Proteomic analysis revealed that proteins involved in cell proliferation, signal transduction, metabolism and protein synthesis were significantly regulated by the availability of iron, rendering a close correlation between cell apoptosis and the disturbance of mitochondrial, signaling and metabolic pathways. These results provide new insights into the mechanisms of cell proliferation inhibition attributed to iron depletion." @default.
- W2052242367 created "2016-06-24" @default.
- W2052242367 creator A5014990417 @default.
- W2052242367 creator A5023302530 @default.
- W2052242367 creator A5038766133 @default.
- W2052242367 creator A5044554947 @default.
- W2052242367 creator A5054489408 @default.
- W2052242367 date "2009-07-01" @default.
- W2052242367 modified "2023-09-30" @default.
- W2052242367 title "Iron depletion decreases proliferation and induces apoptosis in a human colonic adenocarcinoma cell line, Caco2" @default.
- W2052242367 cites W116663061 @default.
- W2052242367 cites W1484891956 @default.
- W2052242367 cites W1494589655 @default.
- W2052242367 cites W1502461041 @default.
- W2052242367 cites W1564880933 @default.
- W2052242367 cites W1967539008 @default.
- W2052242367 cites W1972677660 @default.
- W2052242367 cites W1988917342 @default.
- W2052242367 cites W1997610659 @default.
- W2052242367 cites W1999869813 @default.
- W2052242367 cites W2008883486 @default.
- W2052242367 cites W2016072113 @default.
- W2052242367 cites W2020525844 @default.
- W2052242367 cites W2029635682 @default.
- W2052242367 cites W2035382483 @default.
- W2052242367 cites W2035763080 @default.
- W2052242367 cites W2037032869 @default.
- W2052242367 cites W2047316634 @default.
- W2052242367 cites W2055592070 @default.
- W2052242367 cites W2056688696 @default.
- W2052242367 cites W2071410533 @default.
- W2052242367 cites W2079056345 @default.
- W2052242367 cites W2082175318 @default.
- W2052242367 cites W2090055655 @default.
- W2052242367 cites W2091260254 @default.
- W2052242367 cites W2092776522 @default.
- W2052242367 cites W2096825118 @default.
- W2052242367 cites W2098038194 @default.
- W2052242367 cites W2113999599 @default.
- W2052242367 cites W2114015514 @default.
- W2052242367 cites W2117462796 @default.
- W2052242367 cites W2119272726 @default.
- W2052242367 cites W2120549093 @default.
- W2052242367 cites W2120709879 @default.
- W2052242367 cites W2135295352 @default.
- W2052242367 cites W2138655599 @default.
- W2052242367 cites W2151501496 @default.
- W2052242367 cites W2410507629 @default.
- W2052242367 cites W34816746 @default.
- W2052242367 cites W57040179 @default.
- W2052242367 doi "https://doi.org/10.1016/j.jinorgbio.2009.05.004" @default.
- W2052242367 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19515424" @default.
- W2052242367 hasPublicationYear "2009" @default.
- W2052242367 type Work @default.
- W2052242367 sameAs 2052242367 @default.
- W2052242367 citedByCount "22" @default.
- W2052242367 countsByYear W20522423672012 @default.
- W2052242367 countsByYear W20522423672013 @default.
- W2052242367 countsByYear W20522423672015 @default.
- W2052242367 countsByYear W20522423672016 @default.
- W2052242367 countsByYear W20522423672020 @default.
- W2052242367 countsByYear W20522423672021 @default.
- W2052242367 countsByYear W20522423672022 @default.
- W2052242367 crossrefType "journal-article" @default.
- W2052242367 hasAuthorship W2052242367A5014990417 @default.
- W2052242367 hasAuthorship W2052242367A5023302530 @default.
- W2052242367 hasAuthorship W2052242367A5038766133 @default.
- W2052242367 hasAuthorship W2052242367A5044554947 @default.
- W2052242367 hasAuthorship W2052242367A5054489408 @default.
- W2052242367 hasConcept C1491633281 @default.
- W2052242367 hasConcept C185592680 @default.
- W2052242367 hasConcept C190283241 @default.
- W2052242367 hasConcept C31573885 @default.
- W2052242367 hasConcept C502942594 @default.
- W2052242367 hasConcept C54355233 @default.
- W2052242367 hasConcept C55493867 @default.
- W2052242367 hasConcept C62112901 @default.
- W2052242367 hasConcept C62478195 @default.
- W2052242367 hasConcept C81885089 @default.
- W2052242367 hasConcept C86803240 @default.
- W2052242367 hasConcept C95444343 @default.
- W2052242367 hasConceptScore W2052242367C1491633281 @default.
- W2052242367 hasConceptScore W2052242367C185592680 @default.
- W2052242367 hasConceptScore W2052242367C190283241 @default.
- W2052242367 hasConceptScore W2052242367C31573885 @default.
- W2052242367 hasConceptScore W2052242367C502942594 @default.
- W2052242367 hasConceptScore W2052242367C54355233 @default.
- W2052242367 hasConceptScore W2052242367C55493867 @default.
- W2052242367 hasConceptScore W2052242367C62112901 @default.
- W2052242367 hasConceptScore W2052242367C62478195 @default.
- W2052242367 hasConceptScore W2052242367C81885089 @default.
- W2052242367 hasConceptScore W2052242367C86803240 @default.
- W2052242367 hasConceptScore W2052242367C95444343 @default.
- W2052242367 hasIssue "7" @default.
- W2052242367 hasLocation W20522423671 @default.
- W2052242367 hasLocation W20522423672 @default.
- W2052242367 hasOpenAccess W2052242367 @default.
- W2052242367 hasPrimaryLocation W20522423671 @default.