Matches in SemOpenAlex for { <https://semopenalex.org/work/W2052250073> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2052250073 endingPage "22" @default.
- W2052250073 startingPage "16" @default.
- W2052250073 abstract "Previous work in the mouse and human has shown that removal of cells from 2- and 4-cell embryos disproportionately reduces the inner cell mass (ICM), from which the fetus is derived, suggesting that preimplantation biopsy at these stages would be inadvisable. Here we have examined allocation in twin half mouse embryos produced by bisection at the 8-cell stage. Half embryos and intact zona-free control embryos were differentially labeled at the time of cavitation using polynucleotide-specific fluorochromes, and the numbers of cells in the ICM and trophectoderm (TE) counted. Adding the numbers of cells in the twin halves together, the numbers of ICM cells are not significantly different from those in intact controls. In contrast, numbers of TE cells were significantly higher (P < 0.01), producing a small increase in the total cell number of half embryos. There is no concomitant decrease in ICM cell number. We propose that as the surface area of a half embryo is greater than half an intact control, TE cells in half embryos divide faster in order to reach an optimal packing density similar to that in intact control embryos. Furthermore, we suggest that preimplantation biopsy only be performed at the 8-cell stage or later. © 1993 Wiley-Liss, Inc." @default.
- W2052250073 created "2016-06-24" @default.
- W2052250073 creator A5071761493 @default.
- W2052250073 creator A5082135526 @default.
- W2052250073 date "1993-09-01" @default.
- W2052250073 modified "2023-09-27" @default.
- W2052250073 title "Cell allocation in twin half mouse embryos bisected at the 8-cell stage: Implications for preimplantation diagnosis" @default.
- W2052250073 cites W187023208 @default.
- W2052250073 cites W1934389460 @default.
- W2052250073 cites W1977279131 @default.
- W2052250073 cites W1978373375 @default.
- W2052250073 cites W1978798972 @default.
- W2052250073 cites W2017703255 @default.
- W2052250073 cites W2018122591 @default.
- W2052250073 cites W2023550300 @default.
- W2052250073 cites W2063753069 @default.
- W2052250073 cites W2066630460 @default.
- W2052250073 cites W2067892120 @default.
- W2052250073 cites W2088150245 @default.
- W2052250073 cites W2094425583 @default.
- W2052250073 cites W2107974018 @default.
- W2052250073 cites W2112386362 @default.
- W2052250073 cites W2116073351 @default.
- W2052250073 cites W2139478578 @default.
- W2052250073 cites W2149224534 @default.
- W2052250073 cites W2156057220 @default.
- W2052250073 cites W2184889101 @default.
- W2052250073 cites W2258066394 @default.
- W2052250073 cites W2299540757 @default.
- W2052250073 cites W2321800574 @default.
- W2052250073 cites W32959954 @default.
- W2052250073 cites W951490690 @default.
- W2052250073 doi "https://doi.org/10.1002/mrd.1080360104" @default.
- W2052250073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8398126" @default.
- W2052250073 hasPublicationYear "1993" @default.
- W2052250073 type Work @default.
- W2052250073 sameAs 2052250073 @default.
- W2052250073 citedByCount "17" @default.
- W2052250073 countsByYear W20522500732014 @default.
- W2052250073 countsByYear W20522500732017 @default.
- W2052250073 countsByYear W20522500732022 @default.
- W2052250073 crossrefType "journal-article" @default.
- W2052250073 hasAuthorship W2052250073A5071761493 @default.
- W2052250073 hasAuthorship W2052250073A5082135526 @default.
- W2052250073 hasConcept C1491633281 @default.
- W2052250073 hasConcept C159399396 @default.
- W2052250073 hasConcept C16685009 @default.
- W2052250073 hasConcept C196843134 @default.
- W2052250073 hasConcept C2778177303 @default.
- W2052250073 hasConcept C54355233 @default.
- W2052250073 hasConcept C68760520 @default.
- W2052250073 hasConcept C71924100 @default.
- W2052250073 hasConcept C86803240 @default.
- W2052250073 hasConcept C87073359 @default.
- W2052250073 hasConcept C95444343 @default.
- W2052250073 hasConceptScore W2052250073C1491633281 @default.
- W2052250073 hasConceptScore W2052250073C159399396 @default.
- W2052250073 hasConceptScore W2052250073C16685009 @default.
- W2052250073 hasConceptScore W2052250073C196843134 @default.
- W2052250073 hasConceptScore W2052250073C2778177303 @default.
- W2052250073 hasConceptScore W2052250073C54355233 @default.
- W2052250073 hasConceptScore W2052250073C68760520 @default.
- W2052250073 hasConceptScore W2052250073C71924100 @default.
- W2052250073 hasConceptScore W2052250073C86803240 @default.
- W2052250073 hasConceptScore W2052250073C87073359 @default.
- W2052250073 hasConceptScore W2052250073C95444343 @default.
- W2052250073 hasIssue "1" @default.
- W2052250073 hasLocation W20522500731 @default.
- W2052250073 hasLocation W20522500732 @default.
- W2052250073 hasOpenAccess W2052250073 @default.
- W2052250073 hasPrimaryLocation W20522500731 @default.
- W2052250073 hasRelatedWork W1603060409 @default.
- W2052250073 hasRelatedWork W2002177146 @default.
- W2052250073 hasRelatedWork W2003026164 @default.
- W2052250073 hasRelatedWork W2058310955 @default.
- W2052250073 hasRelatedWork W2114591772 @default.
- W2052250073 hasRelatedWork W2119419499 @default.
- W2052250073 hasRelatedWork W2149811435 @default.
- W2052250073 hasRelatedWork W2586296925 @default.
- W2052250073 hasRelatedWork W2903529700 @default.
- W2052250073 hasRelatedWork W409584878 @default.
- W2052250073 hasVolume "36" @default.
- W2052250073 isParatext "false" @default.
- W2052250073 isRetracted "false" @default.
- W2052250073 magId "2052250073" @default.
- W2052250073 workType "article" @default.